Next Article in Journal
Thalidomide for the Treatment of Gastrointestinal Bleeding Due to Angiodysplasia in a Patient with Glanzmann’s Thrombasthenia
Previous Article in Journal
Invasive Aspergillosis with Disseminated Skin Involvement in a Patient with Acute Myeloid Leukemia: A Rare Case
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Hematology Reports
Volume 9
Issue 2
10.4081/hr.2017.7057
hematolrep-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
Hematology Reports is published by MDPI from Volume 14 Issue 1 (2022). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with PAGEPress.
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Case Report

Acute Myeloid Leukemia with RAM Immunophenotype: A Pediatric Case with Unusual Morphologic Features

by
Miriam Conces
1,
Rolla Abu-Arja
2,
Suzanne Reed
2,
Hemalatha G. Rangarajan
2,
Terri L. Guinipero
2,
Michael R. Loken
3,
Lisa Eidenschink Brodersen
3 and
Samir B. Kahwash
1,*
1
Department of Pathology and Laboratory Medicine, Nationwide Children’s Hospital, 700 Children's Drive, Columbus, OH 43205, USA
2
Division of Hematology/Oncology and Bone Marrow Transplant, Nationwide Children’s Hospital, 700 Children's Drive, Columbus, OH 43205, USA
3
Hematologics, Inc., Seattle, WA 98121, USA
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2017, 9(2), 7057; https://doi.org/10.4081/hr.2017.7057
Submission received: 20 January 2017 / Revised: 15 March 2017 / Accepted: 24 March 2017 / Published: 14 June 2017

Abstract

The RAM immunophenotype has been recently described as a subtype of acute myelogenous leukemia (AML) that is characterized clinically by extremely poor prognosis. We present a case of AML with RAM immunophenotype in a 5-year-old patient that resulted in poor outcome despite early hematopoietic cell transplant. We describe the unusual morphologic features that, along with the distinct immunophenotype, may provide initial diagnostic clues and further justify the classification of this AML variant as a rather distinct subtype.
Keywords: acute myeloid leukemia; pediatric; RAM acute myeloid leukemia; pediatric; RAM

Share and Cite

MDPI and ACS Style

Conces, M.; Abu-Arja, R.; Reed, S.; Rangarajan, H.G.; Guinipero, T.L.; Loken, M.R.; Brodersen, L.E.; Kahwash, S.B. Acute Myeloid Leukemia with RAM Immunophenotype: A Pediatric Case with Unusual Morphologic Features. Hematol. Rep. 2017, 9, 7057. https://doi.org/10.4081/hr.2017.7057

AMA Style

Conces M, Abu-Arja R, Reed S, Rangarajan HG, Guinipero TL, Loken MR, Brodersen LE, Kahwash SB. Acute Myeloid Leukemia with RAM Immunophenotype: A Pediatric Case with Unusual Morphologic Features. Hematology Reports. 2017; 9(2):7057. https://doi.org/10.4081/hr.2017.7057

Chicago/Turabian Style

Conces, Miriam, Rolla Abu-Arja, Suzanne Reed, Hemalatha G. Rangarajan, Terri L. Guinipero, Michael R. Loken, Lisa Eidenschink Brodersen, and Samir B. Kahwash. 2017. "Acute Myeloid Leukemia with RAM Immunophenotype: A Pediatric Case with Unusual Morphologic Features" Hematology Reports 9, no. 2: 7057. https://doi.org/10.4081/hr.2017.7057

Article Metrics

Back to TopTop