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Hematology Reports
Volume 6
Issue 2
10.4081/hr.2014.5356
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Article

Hemophagocytic Lymphohistiocytosis and Pelger-Huët Anomaly Associated with Colchicine Intoxication

by
Baris Malbora
1,*,
Emine Polat
2 and
Sare Gulfem Akyuz
3
1
Department of Pediatric Hematology, Dr. Sami Ulus Research and Training Hospital of Women's and Children’s Health and Diseases, Babur Caddesi 44, Ankara 06080, Turkey
2
Department of Pediatrics, Dr. Sami Ulus Research and Training Hospital of Women's and Children’s Health and Diseases, Ankara, Turkey
3
Department of Pediatric Nephrology, Dr. Sami Ulus Research and Training Hospital of Women's and Children’s Health and Diseases, Ankara, Turkey
*
Author to whom correspondence should be addressed.
Hematol. Rep. 2014, 6(2), 5356; https://doi.org/10.4081/hr.2014.5356
Submission received: 17 February 2014 / Revised: 20 April 2014 / Accepted: 20 May 2014 / Published: 19 June 2014

Abstract

Colchicine is frequently used in the treatment of familial Mediterranean fever (FMF). First symptoms of colchicine intoxication are gastrointestinal disturbances, such as abdominal cramps, diarrhea, pancytopenia and so on. Herein, we report a female FMF patient with pancytopenia and hemophagocytic lymphohitiocytosis (HLH), following colchicine intoxication for committing suicide. To our knowledge, this is the first reported case of a patient with HLH associated with colchicine intoxication.
Keywords: colchicine intoxication; hemophagocytic lymphohitiocytosis; Pelger-Huët anomaly colchicine intoxication; hemophagocytic lymphohitiocytosis; Pelger-Huët anomaly

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MDPI and ACS Style

Malbora, B.; Polat, E.; Akyuz, S.G. Hemophagocytic Lymphohistiocytosis and Pelger-Huët Anomaly Associated with Colchicine Intoxication. Hematol. Rep. 2014, 6, 5356. https://doi.org/10.4081/hr.2014.5356

AMA Style

Malbora B, Polat E, Akyuz SG. Hemophagocytic Lymphohistiocytosis and Pelger-Huët Anomaly Associated with Colchicine Intoxication. Hematology Reports. 2014; 6(2):5356. https://doi.org/10.4081/hr.2014.5356

Chicago/Turabian Style

Malbora, Baris, Emine Polat, and Sare Gulfem Akyuz. 2014. "Hemophagocytic Lymphohistiocytosis and Pelger-Huët Anomaly Associated with Colchicine Intoxication" Hematology Reports 6, no. 2: 5356. https://doi.org/10.4081/hr.2014.5356

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