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Review

Catecholaminergic Polymorphic Ventricular Tachycardia in 2012

by
Ineke Nederend
,
Christian van der Werf
and
Arthur A.M. Wilde
*
Department of Cardiology, Heart Failure Research Center, Academic Medical Center, Amsterdam, The Netherlands
*
Author to whom correspondence should be addressed.
Cardiogenetics 2011, 1(s1), e4; https://doi.org/10.4081/cardiogenetics.2011.s1.e4
Submission received: 28 September 2011 / Revised: 28 September 2011 / Accepted: 14 November 2011 / Published: 20 November 2011

Abstract

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare, potentially lethal inherited arrhythmia syndrome characterized by stress or emotion-induced ventricular arrhythmias. CPVT was first described in 1960, while the genetic basis underlying this syndrome was discovered in 2001. The past decade has seen substantial advances in understanding the pathophysiology of CPVT. In addition, significant advances have been made in elucidating clinical characteristics of CPVT patients and new treatment options have become available. Here, we review current literature on CPVT to present state-of-the-art knowledge on the subject of the genetic basis, pathophysiology, clinical presentation, diagnosis, treatment and prognosis.
Keywords: catecholaminergic polymorphic ventricular tachycardia; sudden cardiac death; genetics; channelopathies catecholaminergic polymorphic ventricular tachycardia; sudden cardiac death; genetics; channelopathies

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MDPI and ACS Style

Nederend, I.; van der Werf, C.; Wilde, A.A.M. Catecholaminergic Polymorphic Ventricular Tachycardia in 2012. Cardiogenetics 2011, 1, e4. https://doi.org/10.4081/cardiogenetics.2011.s1.e4

AMA Style

Nederend I, van der Werf C, Wilde AAM. Catecholaminergic Polymorphic Ventricular Tachycardia in 2012. Cardiogenetics. 2011; 1(s1):e4. https://doi.org/10.4081/cardiogenetics.2011.s1.e4

Chicago/Turabian Style

Nederend, Ineke, Christian van der Werf, and Arthur A.M. Wilde. 2011. "Catecholaminergic Polymorphic Ventricular Tachycardia in 2012" Cardiogenetics 1, no. s1: e4. https://doi.org/10.4081/cardiogenetics.2011.s1.e4

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