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Article
Peer-Review Record

3D-Printing of Capsule Devices as Compartmentalization Tools for Supported Reagents in the Search of Antiproliferative Isatins

Pharmaceuticals 2023, 16(2), 310; https://doi.org/10.3390/ph16020310
by Camilla Malatini 1, Carlos Carbajales 1, Mariángel Luna 2, Osvaldo Beltrán 2, Manuel Amorín 1, Christian F. Masaguer 1, José M. Blanco 1, Silvia Barbosa 2, Pablo Taboada 2,* and Alberto Coelho 1,*
Reviewer 1:
Reviewer 2: Anonymous
Pharmaceuticals 2023, 16(2), 310; https://doi.org/10.3390/ph16020310
Submission received: 31 December 2022 / Revised: 27 January 2023 / Accepted: 9 February 2023 / Published: 16 February 2023
(This article belongs to the Special Issue 3D Printing of Drug Formulations)

Round 1

Reviewer 1 Report

It is a timely effort by authors to conduct a study on "3D-printing of capsule devices as compartmentalization tools for supported reagents in the search of antiproliferative isatins". However, there are few concerns which needs to be addressed.

1.  Novelty should be highlighted in a better way.

2. How results and discussion section is coming before meterials and methods, is this not against a norm of general manuscript settings?

3. What were the 3D printing conditions for sample preparations?

4. The glass transition temperature of PP is usually less than zero. But you mentioned it to be higher see line 211 at page 5.

5. Instead we should talk about the melting point of PP! Why did you not perform the DSC for selected PP?

6. How do you define scheme? You may use the word figure!

7. Write those good properties of PP which are more relevant to this current study.

8. Where are the result of SEM and other microscopic examinations? One cannot find them in the manuscript.

Author Response

Moderate English changes were made in the manuscript.

For the rest of questions, please see the attachment

Author Response File: Author Response.docx

Reviewer 2 Report

Please, see the attached file

Comments for author File: Comments.pdf

Author Response

Please see the attachment

Author Response File: Author Response.docx

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