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Article
Peer-Review Record

Screening and Structural Characterization of Heat Shock Response Elements (HSEs) in Entamoeba histolytica Promoters

Int. J. Mol. Sci. 2024, 25(2), 1319; https://doi.org/10.3390/ijms25021319
by David Dorantes-Palma 1, Salvador Pérez-Mora 1, Elisa Azuara-Liceaga 2, Ernesto Pérez-Rueda 3, David Guillermo Pérez-Ishiwara 1, Misael Coca-González 1, María Olivia Medel-Flores 1 and Consuelo Gómez-García 1,*
Reviewer 1:
Reviewer 2: Anonymous
Int. J. Mol. Sci. 2024, 25(2), 1319; https://doi.org/10.3390/ijms25021319
Submission received: 14 December 2023 / Revised: 9 January 2024 / Accepted: 11 January 2024 / Published: 21 January 2024
(This article belongs to the Special Issue Recent Research on Bioinformatics for Precision Medicine)

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

Dear Authors,

Please check an attached file for my comments.

Best regards,

Comments for author File: Comments.pdf

Author Response

Please see the attachment

Author Response File: Author Response.docx

Reviewer 2 Report

Comments and Suggestions for Authors

This manuscript is a very comprehensive study of the heat shock response elements in the E. histolytica genome. The study is significant in increasing our understanding of the complex survival mechanisms of the parasite. The study is very well done, and I have only a few comments below

 

L38 full genus name (Entamoeba) must be written ant the beginning of the sentence

L108-111 these sentences are more suitable for conclusions. delete or modify as appropriate to the research objectives (L105)

L184-185 Figure 2 caption is missing

L123, 126, 239, 241, 312,484,573 species name must be in italic

L303-304 it is slightly confusing presentation of data, three distinguished groups overlaps and exceeds 100%, this should be reflected in the figure.

L451,480 for biological species avoid such grammatical forms as “E. histolytica's”

Author Response

Please see the attachment.

Author Response File: Author Response.docx

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