Homologous Recombination Deficiencies and Hereditary Tumors
Round 1
Reviewer 1 Report
The article sent for review ,,Homologous Recombination Deficiencies and Hereditary Tumors” is written in a legible and understandable way. The authors describe the issue in detail and modern. In the opinion of the reviewer, the number of literature items is too long and should be shortened. Additionally, authors should provide a certificate confirming the native speaker correction.Author Response
Please see the attachment.
Author Response File: 
Author Response.pdf
Reviewer 2 Report
Comments to authors
The authors did not pay enough attention to the issue of ethnic specificity of germline mutations in homologous repair genes. At the same time, racial differences are known in the variants of repair genes associated with hereditary breast and ovarian cancer in individuals from different ethnic groups. Such an analysis would be useful and would justify the need to search for germline mutations in the repair genes, which may differ in patients belonging to different races: Caucasian, Mongoloid, and Negroid.
It would be desirable authors to shortly analyze ethnic specificity for germline variants of HR genes in different populations.
The manuscript may be accepted after minor revision taking into account the ethnic and race differences in germline alterations in HR related gene associated with hereditary cancer syndrome.
Comments for author File: 
Comments.docx
Author Response
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Author Response File: Author Response.pdf
