Special Issues

Cells publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Melanoma: From Molecular Mechanisms to Therapeutic Opportunities—Series 2 submission deadline 30 May 2024 | 2 articles | Viewed by 2002 | Submission Open
Keywords: melanomagenesis; treatment response; signal transduction; melanoma initiating cells; drug resistance; invasiveness; immune evasion; metastasis; MAPK pathway; PI3K/AKT survival pathways; MEKi; BRAFi; trametinib; dabrafenib; immunotherapies
(This special issue belongs to the Section Cellular Pathology)
Metabolic Regulation of Hematopoietic Stem Cells
edited by
submission deadline 30 May 2024 | 1 articles | Viewed by 1353 | Submission Open
Keywords: hematopoietic stem cells; metabolic regulation; mitochondrial function; self-renewal and differentiation; quiescence; energy metabolism; HSC exhaustion; aging; bm niche; leukemia stem cells (LSCs)
(This special issue belongs to the Section Stem Cells)
CRISPR/Cas9-Mediated Gene Therapy in Cancer
edited by , Subhajit Giri and Sharad Awasthi
submission deadline 30 May 2024 | Viewed by 623 | Submission Open
Keywords: CRISPR/Cas; liquid tumor; solid-state cancer; gene therapy; AAV; CAR-T; lipid nanoparticle; immunotherapy; cytotoxicity
(This special issue belongs to the Section Cell Methods)
The Role of Histological Techniques in Neuroscience and Neural Engineering
edited by and Fernando Campos Sánchez
submission deadline 30 May 2024 | Viewed by 206 | Submission Open
Keywords: nerve tissue histology; histochemistry; immunohistochemistry; metal reduction techniques; light & electron microscopy; morphometric analyses; tissue engineering; nerve regeneration; neural degeneration; demyelinating diseases
(This special issue belongs to the Section Tissues and Organs)
Role of Innate Immunity in Chronic Kidney Diseases—Series 2
edited by
submission deadline 30 May 2024 | Viewed by 137 | Submission Open
Keywords: CKD; glomeruli; tubules; sterile inflammation; innate immunity; pattern recognition receptors (PRRs); damage-associated molecular patterns (DAMPs); STING; toll-like receptors; RIG-I; NLRP
(This special issue belongs to the Section Cellular Immunology)
Signaling Pathways in Pregnancy submission deadline 31 May 2024 | 12 articles | Viewed by 24610 | Submission Open
Keywords: cell signaling; proliferation; differentiation; invasion; placentation; placenta; trophoblast; preeclampsia; fetal growth restriction; gestational diabetes mellitus
(This special issue belongs to the Section Cell Signaling)
Advances in Muscle Research in Health and Disease
edited by
submission deadline 31 May 2024 | 5 articles | Viewed by 9860 | Submission Open
Keywords: skeletal muscle; cardiac muscle; smooth muscle; myocyte; vascular smooth muscle cell; stem cell; development; homeostasis; regeneration; biomarker; therapeutic target
(This special issue belongs to the Section Cell Signaling)
Autophagy and Apoptosis in Skeletal Muscle submission deadline 31 May 2024 | 2 articles | Viewed by 5387 | Submission Open
Keywords: autophagy; apoptosis; skeletal muscle; cell signaling; mitochondria; myopathies; sarcopenia; atrophy; immune system; therapeutic strategies
(This special issue belongs to the Section Autophagy)
Cellular Reprogramming during Sepsis and Potential Therapeutic Targets submission deadline 31 May 2024 | 2 articles | Viewed by 4810 | Submission Open
(This special issue belongs to the Section Cellular Pathology)
Cellular and Molecular Mechanisms Underlying Large-Vessel Vasculitis
edited by and Francesco Muratore
submission deadline 31 May 2024 | 3 articles | Viewed by 4554 | Submission Open
Keywords: large-vessel vasculitis; giant cell arteritis; Takayasu’ s arteritis; Behcet’ s Disease; in vitro/animal models; novel therapy
(This special issue belongs to the Section Cells of the Cardiovascular System)
Muscle Homeostasis and Regeneration: From Molecular Mechanisms to Therapeutic Opportunities—Series II submission deadline 31 May 2024 | 3 articles | Viewed by 4542 | Submission Open
Keywords: muscle homeostasis; muscle regeneration; satellite cells; stem cells; FAPs; tissue niche; growth factors; inflammatory response; muscle pathology; aging
(This special issue belongs to the Section Cellular Pathology)
The Applications of Flow Cytometry: Advances, Challenges, and Trends
edited by
submission deadline 31 May 2024 | 1 articles | Viewed by 4527 | Submission Open
Keywords: flow cytometry; single cell; cell function; T-cell subset
(This special issue belongs to the Section Cell Methods)
The Current Applications and Potential of Stem Cell-Derived Organoids submission deadline 31 May 2024 | 2 articles | Viewed by 3505 | Submission Open
Keywords: organoids; stem cell-derived organoids; stem cells; pluripotent stem cells; iPSCs; organ-on-a-chip; disease modelling; cellular therapeutics; regenerative medicine
(This special issue belongs to the Section Stem Cells)
MicroRNA as Biomarker in Carcinoma Cell
edited by , and Eduardo López-Urrutia
submission deadline 31 May 2024 | 2 articles | Viewed by 2829 | Submission Open
Keywords: carcinoma cell; microRNA; prognosis; diagnoses; molecular biomarker; methods for detection; miRNA targets
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Viruses and Cancer: From Cellular Mechanism to Therapeutic Aspects submission deadline 31 May 2024 | 1 articles | Viewed by 2738 | Submission Open
Keywords: virus-induced cancer; host stress responses; DNA damage response; virus– host interactions; autophagy; cellular innate immunity; cell metabolism; immune evasion mechanisms; inflammation; therapeutic approach
(This special issue belongs to the Section Cell Microenvironment)
Cell Biology: State-of-the-Art and Perspectives in China
edited by Di Chen and
submission deadline 31 May 2024 | 1 articles | Viewed by 2658 | Submission Open
Regulatory Programs of Skeletal Muscle Repair and Regeneration submission deadline 31 May 2024 | 1 articles | Viewed by 1787 | Submission Open
Research on Proteomics and Its Applications in Disease
edited by
submission deadline 31 May 2024 | 1 articles | Viewed by 1695 | Submission Open
Keywords: bottom-up proteomics; top-down proteomics; spatial proteomics; bioinformatics; human diseases; cancer; viral infections; bacterial infections; rare pathologies
(This special issue belongs to the Section Cell Methods)
Highlights in Red Blood Cell Research submission deadline 31 May 2024 | 2 articles | Viewed by 1671 | Submission Open
Keywords: red blood cells; anemia; transfusion; erythropoiesis; signaling
Cancer Stem Cells and Immunotherapy submission deadline 31 May 2024 | Viewed by 646 | Submission Open
Keywords: cancer stem cells; CSC-specific biomarkers; immunotherapies; signaling transduction pathways; tumor microenvironment; metastasis; therapy resistance; DNA repair; cellular metabolism; combination therapies
(This special issue belongs to the Section Cellular Immunology)
The Role of Apoptosis in Tissue Homeostasis, Malignancies, and Disease Pathogenesis submission deadline 31 May 2024 | 1 articles | Viewed by 456 | Submission Open
Keywords: apoptosis; cell death; p53 pathway; autophagy; caspase; mitochondria; neurodegeneration; inflammation; drug discovery; cancer; targeted anticancer therapy; autoimmunity; nanodelivery
(This special issue belongs to the Section Autophagy)
Cellular and Molecular Alterations in the Down Syndrome Brain: A Starting Point for the Design of Therapeutic Approaches submission deadline 31 May 2024 | Viewed by 268 | Submission Open
Keywords: down syndrome; cellular defects; deranged molecular pathways; altered neurodevelopment; neurodegeneration; effects of therapies
(This special issue belongs to the Section Cellular Pathology)
Organogenesis and Regeneration: From Basic Research to Medical Study submission deadline 31 May 2024 | Viewed by 248 | Submission Open
Keywords: organogenesis; regeneration; development; proliferation; differentiation; blastema; signaling pathway
(This special issue belongs to the Section Tissues and Organs)
Mitochondria Meets Oxidative Stress submission deadline 31 May 2024 | Viewed by 244 | Submission Open
Keywords: mitochondria; oxidative stress; reactive oxygen species (ROS); cellular respiration; antioxidant defense; ageing
(This special issue belongs to the Section Mitochondria)
Synapses: Molecular Organization, Regulation and Synaptic Function
edited by Houhui Xia
submission deadline 31 May 2024 | Viewed by 211 | Submission Open
Keywords: synapse; glutamate; GABA; neurotransmitter receptor; scaffolding protein; ion channel; kinase; phosphatase; cell adhesion molecule
(This special issue belongs to the Section Cells of the Nervous System)
Gene Editing in Stem Cells: Next-Generation Stem Cell Therapies
edited by
submission deadline 31 May 2024 | Viewed by 180 | Submission Open
Keywords: gene editing; stem cells; CRISPR/Cas system; ZFN; TALEN
(This special issue belongs to the Section Stem Cells)
Pathophysiological Mechanisms of Cholestatic and Metabolic-Associated Fatty Liver Disease
edited by
submission deadline 31 May 2024 | Viewed by 174 | Submission Open
Keywords: steatosis; steatohepatitis; bile flux; inflammation; FXR
(This special issue belongs to the Section Cellular Pathology)
The Signaling and Cellular Mechanisms of Pain—Second Edition
edited by
submission deadline 31 May 2024 | Viewed by 174 | Submission Open
Keywords: nociception; neuropathic pain; visceral pain; pain pathophysiological pathways; glia; analgesia
Role of Hyaluronan in Human Health and Disease
edited by Barbara Triggs-Raine and
submission deadline 31 May 2024 | Viewed by 171 | Submission Open
Keywords: hyaluronan; hyaluronidases; hyaluronan-binding proteins; hyaluronan receptors; fibrosis; cancer; development; immune function
Pain: Neurobiology, Pathophysiology, and Therapeutic Approaches
edited by Joshua W. Little
submission deadline 31 May 2024 | Viewed by 171 | Submission Open
Keywords: pain; pain pathophysiology; neurobiology; nonopioid therapy; acute pain; chronic pain
(This special issue belongs to the Section Cellular Pathology)
T-Cell Acute Lymphoblastic Leukaemia submission deadline 31 May 2024 | Viewed by 163 | Submission Open
Keywords: T-cell leukemias; molecular pathogenesis; immune phenotype; T-cell leukemia epidemiology; T-cell ontogeny; transplantation in T-cell leukemia; target therapies
(This special issue belongs to the Section Cellular Immunology)
Pathophysiology of Central Nervous System Tumors
edited by Mariëtte E.G. Kranendonk
submission deadline 31 May 2024 | Viewed by 135 | Submission Open
Keywords: CNS tumor; pediatric; adult; molecular profiling; multiomics; microenvironment
(This special issue belongs to the Section Cellular Pathology)
Regulation Mechanisms of Myogenic and Cardiomyogenic Differentiation II
edited by
submission deadline 31 May 2024 | Viewed by 123 | Submission Open
Keywords: stem cells; myogenic differentiation; cardiomyogenic differentiation; regeneration; model systems
Inflammatory Processes in Healthy and Diseased Brains
edited by
submission deadline 1 Jun 2024 | 1 articles | Viewed by 2336 | Submission Open
Keywords: immune response; neurodegeneration; microglia; inflammation; lymphocytes
(This special issue belongs to the Section Cells of the Nervous System)
Metabolic Adaptation Processes in Cancer: Transcriptomic, Proteomic and Metabolomic Studies submission deadline 1 Jun 2024 | Viewed by 331 | Submission Open
Keywords: cancer cell metabolism; inflammation; anticancer drugs; tumor-specific metabolic biomarkers; oxidative stress; omics sciences applied to cancer research; tumor immune microenvironment
(This special issue belongs to the Section Cellular Metabolism)
Gene and Cell Therapy in Regenerative Medicine—Second Edition submission deadline 10 Jun 2024 | 7 articles | Viewed by 9860 | Submission Open
Keywords: gene therapy; cell therapy; regenerative medicine; growth factors; stem cells
(This special issue belongs to the Section Cell and Gene Therapy)
Glioblastoma Cell: From Cellular and Molecular Mechanisms to Innovative Therapy
edited by
submission deadline 10 Jun 2024 | 3 articles | Viewed by 5150 | Submission Open
Keywords: glioblastoma cell line; adjuvant substance; target therapy; molecular pathways; molecular markers; GSCs
(This special issue belongs to the Section Cellular Pathology)
Liver Constituent Cells: Their Niche, Close Intercellular Relationship and Crosstalk with the Extracellular Environment—Current and Future Perspectives (2nd Edition) submission deadline 10 Jun 2024 | Viewed by 119 | Submission Open
Keywords: chronic liver diseases; liver microcirculatory milieu; liver sinusoidal endothelial cells (LSECs); hepatic stellate cells (HSCs); Kupffer cells; hepatocytes; cholangiocytes; sinusoid capillarization; Disse space
(This special issue belongs to the Section Tissues and Organs)
Review Papers in (Re)programming Cells for Cardiac Repair
edited by and
submission deadline 15 Jun 2024 | 4 articles | Viewed by 10883 | Submission Open
Keywords: cardiac programming; cardiogenesis; transcriptional regulation; epigenetics; cardiac tissue engineering
(This special issue belongs to the Section Cells of the Cardiovascular System)
Extracellular Vesicles in Health and Disease 2023 submission deadline 15 Jun 2024 | 5 articles | Viewed by 8473 | Submission Open
Keywords: extracellular vesicles; cancer; cardiovascular diseases; neurodegenerative diseases; autoimmunity and transplantation; innate immunity and inflammation; immunoregulation; infectious diseases
(This special issue belongs to the Section Cellular Pathology)
Hypothalamic Hormonal Secretion and Metabolism
edited by
submission deadline 15 Jun 2024 | 2 articles | Viewed by 4952 | Submission Open
Keywords: hypothalamus; endocrine control; energy homeostasis; hormones; signaling
(This special issue belongs to the Section Cellular Metabolism)
Forkhead-Box (Fox)O Family Transcription Factors in Cancer submission deadline 15 Jun 2024 | 1 articles | Viewed by 1516 | Submission Open
Keywords: forkhead-box class O transcription factors; cancer; apoptosis; tumor progression; EMT; gene transcription; drug resistance; endocrine therapy; lnRNA; PTMs
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Large-Scale Multi-Omic Approaches and Atlas-Based Profiling for Cellular, Molecular, and Functional Specificity, Heterogeneity, and Diversity in the Endocannabinoid System
edited by and
submission deadline 15 Jun 2024 | 1 articles | Viewed by 1184 | Submission Open
Keywords: lipidomics; proteomics; transcriptomics; cluster analysis; massive parallel screening; molecular markers; brain circuits; development; neural plasticity; synapse; appetite and feeding behavior; addiction; pain; epilepsy; neurological disorders
(This special issue belongs to the Section Cells of the Nervous System)
Role of Autophagy in Plant Cells
edited by
submission deadline 15 Jun 2024 | Viewed by 368 | Submission Open
Keywords: autophagy; endoplasmic reticulum; TOR; vacuoles; lysosomes; mitochondria; plastids
(This special issue belongs to the Section Plant, Algae and Fungi Cell Biology)
Epigenetics of Brain Function and Diseases submission deadline 15 Jun 2024 | Viewed by 341 | Submission Open
Keywords: neurodevelopmental; neurological; neuropsychiatric; and neurodegenerative disorders; DNA methylation; chromatin remodeling; histone modifications; non-coding RNA; transcriptome; epigenome; epigenetic writers; readers and erasers
(This special issue belongs to the Section Cell Nuclei: Function, Transport and Receptors)
Melanoma and Non-melanoma Skin Cancer: Cellular Mechanisms, Immunity and Therapeutics
edited by
submission deadline 15 Jun 2024 | Viewed by 226 | Submission Open
Keywords: melanoma; squamous cell carcinoma; Merkel cell carcinoma; tumorigenicity; metastasis; therapeutic targets
(This special issue belongs to the Section Cellular Immunology)
Oxidative Stress in Aging and Neurodegenerative Diseases—Series 2
edited by
submission deadline 15 Jun 2024 | Viewed by 167 | Submission Open
Keywords: aging; oxidative stress; antioxidant; Alzheimer’ s disease; Parkinson’ s disease; Lou Gehrig’ s disease; drug discovery
(This special issue belongs to the Section Cellular Aging)
Tooth-Related Stem Cells and Regenerative Medicine
edited by and Masaki Honda
submission deadline 15 Jun 2024 | Viewed by 107 | Submission Open
Keywords: mesenchymal stem cells; neural crest cells; bone marrow; adipose tissue; cell proliferation; cell differentiation; signal transduction; extracellular matrix; growth factors; cell culture; scaffolds; cell sheets; preservation; transplantation; bone; dentin; cartilage; tooth; tissue engineering
(This special issue belongs to the Section Stem Cells)
Reprogrammed Cells in Disease Modeling and Drug Discovery II
edited by
submission deadline 20 Jun 2024 | 6 articles | Viewed by 10714 | Submission Open
Keywords: patient-derived cells; iPS (induced pluripotent stem cells); CRC (conditionally reprogrammed cells); organoids; air– liquid interface cultures; circulating tumor cells; human diseases; disease modeling; cancer models; drug discovery
(This special issue belongs to the Section Cell and Gene Therapy)
Molecular Mechanisms of Aging in Cardiovascular Disease
edited by Gloria Salazar
submission deadline 20 Jun 2024 | 1 articles | Viewed by 1894 | Submission Open
Keywords: senescence; atherosclerosis; oxidative stress; inflammation
(This special issue belongs to the Section Cellular Pathology)
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