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Veterinary Sciences
Special Issues
Genetic and Epigenetic Mechanisms of Animals Retrovirus Diseases
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Genetic and Epigenetic Mechanisms of Animals Retrovirus Diseases

A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Veterinary Microbiology, Parasitology and Immunology".

Deadline for manuscript submissions: closed (15 December 2022) | Viewed by 3844

Special Issue Editors

Prof. Dr. Hengmi Cui

E-Mail Website
Guest Editor
Institute of Epigenetics and Epigenomics, College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
Interests: cancer; epigenetics; endogenous retrovirus; lncRNA
Prof. Dr. Zhihua Jiang

E-Mail Website
Guest Editor
Department of Animal Sciences, Washington State University, Pullman, WA, USA
Interests: genetics; comparative genomics; phenomics; alternative transcriptomics; animal

Special Issue Information

Dear Colleagues,

We are pleased to invite you to submit an article to our Special Issue “Genetic and Epigenetic Mechanisms of Animal Retrovirus Diseases”.

Retroviruses can cause many animal diseases, including avian leukemia virus (ALV) and avian reticulosis virus (REV). Because retroviruses are easy to mutate, so far, there is no effective vaccine for diseases caused by such kinds of viruses, such as avian leukemia. Therefore, avian leukemia is still prevalent and is one of the main threats to poultry production. Interestingly, recent studies have found that there are many endogenous retrovirus sequences with high homology with exogenous retrovirus in the animal genome, but its functions, especially its antiviral function, need to be identified. In order to effectively control the diseases caused by retroviruses, it is very important to study the genetic and epigenetic mechanisms of pathogenesis and the interaction between retrovirus and the host.

This Special Issue aims to study the genetic and epigenetic mechanisms of animal diseases caused by retroviruses and animal antiviral phenotypes. Original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Animal diseases caused by retroviruses;
  • Vaccine development for animal retrovirus;
  • Antiviral function of endogenous retroviral elements;
  • Innate immunity function of animal endogenous retroviruses;
  • Epigenetic regulation of animal endogenous retroviruses;
  • Genomics of susceptible animals to retroviruses;
  • Animal antiviral breeding against retroviruses;
  • Identification of biomarkers for anti-retroviral breeding;
  • Host–retrovirus interaction;
  • Functions of ERV-derived lncRNAs.

We look forward to receiving your contributions.

Prof. Dr. Hengmi Cui
Prof. Dr. Zhihua Jiang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Veterinary Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • animal diseases caused by retroviruses
  • vaccine development for animal retrovirus
  • antiviral function of endogenous retroviral elements
  • innate immunity function of animal endogenous retroviruses
  • epigenetic regulation of animal endogenous retroviruses
  • genomics of susceptible animal to retroviruses
  • animal antiviral breeding against retroviruses
  • identification of biomarkers for anti-retroviral breeding
  • host–retrovirus interaction
  • functions of ERV-derived lncRNAs

Published Papers (2 papers)

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Research

11 pages, 1467 KiB  
Communication
Influence of BoLA-DRB3 Polymorphism and Bovine Leukemia Virus (BLV) Infection on Dairy Cattle Productivity
by Ayumi Nakatsuchi, Yasunobu Matsumoto and Yoko Aida
Vet. Sci. 2023, 10(4), 250; https://doi.org/10.3390/vetsci10040250 - 27 Mar 2023
Cited by 1 | Viewed by 1421
Abstract
Enzootic bovine leukosis caused by the bovine leukemia virus (BLV) results in substantial damage to the livestock industry; however, we lack an effective cure or vaccine. BoLA-DRB3 polymorphism in BLV-infected cattle is associated with the proviral load (PVL), infectivity in the blood, development [...] Read more.
Enzootic bovine leukosis caused by the bovine leukemia virus (BLV) results in substantial damage to the livestock industry; however, we lack an effective cure or vaccine. BoLA-DRB3 polymorphism in BLV-infected cattle is associated with the proviral load (PVL), infectivity in the blood, development of lymphoma, and in utero infection of calves. Additionally, it is related to the PVL, infectivity, and anti-BLV antibody levels in milk. However, the effects of the BoLA-DRB3 allele and BLV infection on dairy cattle productivity remain poorly understood. Therefore, we investigated the effect of BLV infection and BoLA-DRB3 allele polymorphism on dairy cattle productivity in 147 Holstein dams raised on Japanese dairy farms. Our findings suggested that BLV infection significantly increased milk yield. Furthermore, the BoLA-DRB3 allele alone, and the combined effect of BLV infection and the BoLA-DRB3 allele had no effect. These results indicate that on-farm breeding and selection of resistant cattle, or the preferential elimination of susceptible cattle, does not affect dairy cattle productivity. Additionally, BLV infection is more likely to affect dairy cattle productivity than BoLA-DRB3 polymorphism. Full article
(This article belongs to the Special Issue Genetic and Epigenetic Mechanisms of Animals Retrovirus Diseases)
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13 pages, 2516 KiB  
Article
Global Maps of Avian Leukosis Viruses: Research Trends and Themes Based on Networking
by Gul Zaib, Xuming Hu and Hengmi Cui
Vet. Sci. 2023, 10(1), 16; https://doi.org/10.3390/vetsci10010016 - 26 Dec 2022
Cited by 2 | Viewed by 1494
Abstract
Avian leukosis virus (ALV) has a tremendous adverse impact on the poultry industry. Since its discovery, research on different aspects of ALV have been published. Due to the vast academic emphasis and economic importance of the ALV infection in poultry worldwide, this bibliometric [...] Read more.
Avian leukosis virus (ALV) has a tremendous adverse impact on the poultry industry. Since its discovery, research on different aspects of ALV have been published. Due to the vast academic emphasis and economic importance of the ALV infection in poultry worldwide, this bibliometric analysis explored the scientific output associated with ALV utilizing the Web of Science (Core Collection) database. The relevant data were collected using the search query “AVIAN LEUKOSIS VIRUS”, further refined by document types (article, book chapter, and proceedings paper). Finally, 1060 items with full records were imported in Plaintext and tab-delimited formats. The data analysis was carried out using MS Excel, VOS viewer, and R (Biblioshiny) software. Chinese and American research institutions produced the majority of papers during study time period. The Journal of Virology and Avian Diseases appeared as the favorite journal/source for publications. Apart from the avian leukosis virus and the ALV-J, the important keywords mentioned included avian leukosis virus subgroup j, chicken, and retrovirus. The analysis revealed substantial findings on ALV research, with a strong research response from the USA and China. Full article
(This article belongs to the Special Issue Genetic and Epigenetic Mechanisms of Animals Retrovirus Diseases)
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