Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
2.3
2.4
Journals
Veterinary Sciences
Special Issues
Endocrine and Metabolic Regulation in Male Animal Reproduction
share announcement

Endocrine and Metabolic Regulation in Male Animal Reproduction

A special issue of Veterinary Sciences (ISSN 2306-7381). This special issue belongs to the section "Veterinary Reproduction and Obstetrics".

Deadline for manuscript submissions: 20 June 2024 | Viewed by 4530

Special Issue Editors

Dr. Anna Costagliola

E-Mail Website
Guest Editor
Department of Veterinary Medicine and Animal Productions, University of Napoli Federico II, 80100 Naples, Italy
Interests: immunohistochemistry; western blot analysis; gel electrophoresis; cell culture; animal anatomy
Dr. Giovanna Liguori

E-Mail Website
Guest Editor
Department of Veterinary Medicine and Animal Productions, University of Napoli Federico II, 80100 Naples, Italy
Interests: immunofluorescence; immunohistochemistry; receptors; spermatogenesis; hypothalamus; testis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Sexual hormones are often major regulators of complex behaviors, such as mating and reproduction. Traditionally, androgens, as genital male hormones, regulate such functions. Neuropeptides, neurotransmitters, growth factors and cytokines are expressed in the reproductive organs and tissues of many animal species, both in physiological and pathological conditions; here, they interact with afferent endocrine messages in order to modulate cell proliferation and differentiation, and local hormone secretion. These peptides, together with other internal or external environmental factors and/or chemicals, have the capacity to interfere with normal signalling systems by blocking or modulating the synthesis, release, transport, metabolism, binding or elimination of the sexual hormones.

We welcome publications that explore the role and the effects of these external and internal modulators that act on the reproductive functions of different male animal species.

Suitable topics include:

- Anatomical studies

- Functional studies

- Comparative studies

- Tissue tests

Original articles, Reviews and Case Report articles will be considered.

Dr. Anna Costagliola
Dr. Giovanna Liguori
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Veterinary Sciences is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (3 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Review

13 pages, 1203 KiB  
Article
Age-Related Differences in Testosterone Concentration and Its Relation to Testicular Biometrics, Hemodynamics, and Fertility in Alpacas (Vicugna pacos)
by Manuel G. Pérez-Durand, Angela Massa-Guzmán, Natalio Luque-Mamani, Domingo A. Ruelas-Calloapaza, Jesús M. Urviola-Sánchez, Eloy A. Condori-Chuchi, Miguel A. Gutiérrez-Reinoso, Uri H. Perez-Guerra and Manuel García-Herreros
Vet. Sci. 2023, 10(7), 429; https://doi.org/10.3390/vetsci10070429 - 01 Jul 2023
Viewed by 1520
Abstract
The goal of this study was to investigate the age-related differences in testosterone concentration and its relation to testicular biometrics, testicular blood flow, and fertility in alpacas (Vicugna pacos). Fifteen alpaca males with different ages (young (YM; ~12–14 mo.), n = [...] Read more.
The goal of this study was to investigate the age-related differences in testosterone concentration and its relation to testicular biometrics, testicular blood flow, and fertility in alpacas (Vicugna pacos). Fifteen alpaca males with different ages (young (YM; ~12–14 mo.), n = 5; intermediate (IM; ~24 mo.), n = 5; and old (OM; ≥36 mo.), n = 5) were enrolled in the study. Blood samples were taken from each alpaca male and the circulating plasmatic testosterone concentration (TC; ng/mL) was determined using ELISA analysis. The testicular traits related to bio-morphometric parameters (the length (L), width (W), area (A), and volume (TV)) were assessed using B-mode ultrasonography. Pulse-wave/power Doppler ultrasonography was used to obtain the circulatory dynamic values (testicular hemodynamics) before the beginning of natural service mating. Significant differences were observed in TC among the age groups, increasing as the age of the males increased (2.47 ± 0.31, 8.45 ± 1.53, and 22.66 ± 2.15 for YM, IM, and OM, respectively; p < 0.05); however, no differences were observed regarding the testicular B-mode ultrasonographic parameters (L, W, and A) (p > 0.05). Positive correlations were observed between TV and testicular L, W, and A (r = 0.96, r = 0.95, and r = 0.96, respectively; p ≤ 0.001). Pulse-wave-Doppler-derived parameters such as the pulsatility index (PI) and the resistive index (RI), as well as the total vascularity area (TVA) assessed by power Doppler, were similar in all of the age groups studied (p > 0.05). General linear model (GLM) analysis showed a relationship between TC and TV (OR = 0.95; p = 0.04), as well as between TC and TVA (OR = 0.99; p= 0.02). Finally, no differences were observed regarding the pregnancy rate among the different age groups (p > 0.05). In conclusion, TC increased as the age of the alpaca males increased. Although TC was related to TV and TVA, the pregnancy rates obtained from individuals belonging to the different age groups were similar, indicating that TC, TV, and TVA were not determining factors in assessing the potential age-related fertility differences in alpaca males. Full article
(This article belongs to the Special Issue Endocrine and Metabolic Regulation in Male Animal Reproduction)
►▼ Show Figures

Figure 1

9 pages, 596 KiB  
Article
Incorporation of Testicular Ultrasonography and Hair Steroid Concentrations in Bull Breeding Soundness Evaluation
by Alessio Cotticelli, Luigi Navas, Alfonso Calabria, Giovanna Bifulco, Giuseppe Campanile, Tanja Peric, Alberto Prandi, Michael J. D’Occhio and Marco Russo
Vet. Sci. 2023, 10(6), 373; https://doi.org/10.3390/vetsci10060373 - 25 May 2023
Viewed by 1015
Abstract
Testicular ultrasonography and steroid concentrations (cortisol, dehydroepiandrosterone sulfate (DHEA-S), cortisol/DHEA-S ratio, testosterone) in hair were examined for their utility in the bull breeding soundness evaluation (BBSE). Beef and dairy bulls (n = 16; 2.7 ± 0.4 years old; body condition score 3.2 [...] Read more.
Testicular ultrasonography and steroid concentrations (cortisol, dehydroepiandrosterone sulfate (DHEA-S), cortisol/DHEA-S ratio, testosterone) in hair were examined for their utility in the bull breeding soundness evaluation (BBSE). Beef and dairy bulls (n = 16; 2.7 ± 0.4 years old; body condition score 3.2 ± 0.1) of five breeds were maintained under the same conditions at an accredited semen collection center. Bulls underwent routine semen collection twice weekly for 12 weeks and semen was processed and cryopreserved. Ultrasonography and hair sampling were undertaken at the last semen collection. Bulls with homogeneous testicular parenchyma (n = 8) had a higher (p < 0.05) percentage of motile sperm post-thawing compared with bulls with heterogeneous parenchyma (n = 8). There were no differences (p > 0.05) in the hair concentrations of cortisol, DHEA-S, and testosterone between bulls with homogeneous and heterogeneous parenchyma. In bulls with homogeneous parenchyma, hair DHEA-S concentration was positively correlated with percentage motile sperm (R2 = 0.76), progressively motile sperm (R2 = 0.70), and motility yield (R2 = 0.71). The findings indicate that the integration of testicular ultrasonography and hair DHEA-S status in the BBSE could provide a more comprehensive assessment of indicative fertility in bulls. Additionally, ultrasonography can be used in the BBSE when the evaluation of semen parameters is not available. Full article
(This article belongs to the Special Issue Endocrine and Metabolic Regulation in Male Animal Reproduction)
►▼ Show Figures

Figure 1

Review

Jump to: Research

19 pages, 352 KiB  
Review
A Comparative Analysis of Orexins in the Physio-Pathological Processes of the Male Genital Tract: New Challenges? A Review
by Anna Costagliola, Luigi Montano, Emilia Langella, Renato Lombardi, Caterina Squillacioti, Nicola Mirabella and Giovanna Liguori
Vet. Sci. 2024, 11(3), 131; https://doi.org/10.3390/vetsci11030131 - 15 Mar 2024
Viewed by 1166
Abstract
Orexins A (OXA) and B (OXB) and their specific receptors, receptor 1 (OX1R) and 2 (OX2R) for orexins, are hypothalamic peptides involved in orchestrating several functions in the central nervous system and peripheral organs, including sleep, excitement, nutrition, reward, circadian rhythm, anxiety, cognition, [...] Read more.
Orexins A (OXA) and B (OXB) and their specific receptors, receptor 1 (OX1R) and 2 (OX2R) for orexins, are hypothalamic peptides involved in orchestrating several functions in the central nervous system and peripheral organs, including sleep, excitement, nutrition, reward, circadian rhythm, anxiety, cognition, and reproduction. The aim of this narrative review is, in particular, to speculate the role of orexins in the male genital tract of animal species and human beings. The experimental evidence collected in recent years assumed that in the testes of the animal species here described, orexins are directly involved in steroidogenesis and spermatogenesis regulation. In the epididymis, these peptides are locally synthesized, thus suggesting their role governing the fertilizing capability of the immature male gamete. In addition to playing a physiological role, orexins are involved in numerous inflammatory and/or neoplastic pathologies too. The expression of the orexinergic system in prostate cancer suggests that they might play a potential therapeutic function. Overall, the future directions of this literature review allow us to hypothesize a role of the orexinergic complex not only as a marker for the diagnosis of certain tumors affecting the male genital tract but also for the treatment of hypo/infertility condition. Full article
(This article belongs to the Special Issue Endocrine and Metabolic Regulation in Male Animal Reproduction)
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-3
Back to TopTop