Special Issue "Role of Integrative Genomics Surveillance in Viruses Understanding for Efficient Vaccine Development"

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "DNA and mRNA Vaccines".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 130

Special Issue Editor

1. Principal Scientist, CSIR-Institute of Genomics and Integrative Biology (CSIR-IGIB), Mall Road Campus, Delhi 110007, India
2. Associate Professor, Academy of Scientific and Innovative Research (AcSIR), Chennai 600113, India
Interests: pathogens’ genomes; human host response; co-infections; non-coding RNA; cellular heterogeneity; effective Immune response

Special Issue Information

Dear Colleagues

Viruses are diverse in terms of genome size and genetic backbone (DNA/RNA), dynamic in terms of evolving variants (variants of concern, variants of interest) and cause differential disease manifestations (mild, moderate, severe) in infected individuals. This has been highlighted more than ever before during the COVID-19 pandemic, which challenged global public health, medical and healthcare support. However, at the same time, genomic surveillance has greatly aided and augmented shared learning of the different facets of the virus with a functional role in clinical outcome (recovered/mortality). It greatly helped the development of a vaccine with the aim of preventing infection or milder disease severity if infected. As we prepare for potential future pandemics, the combination of pre-emptive pathogen surveillance and equitable vaccination strategy may be a step towards timely collective response for virus/es of concern. Genomic surveillance holds the potential to also discover/detect the secondary infections that may be modulating the disease severity and outcome, in addition to understanding the instances of vaccination breakthroughs in a subset of vaccinated individuals. Taken together, genomics-based insights would augment vaccination efficacy and refine the strategy (if required), taking into account the evolution of the virus captured through genomic surveillance.

The Special Issue aims at bringing together different aspects of genomics-based research through a combination of original research and review articles.

  • Viral genome features;
  • Differential immune escape potentials of VOCs by the presence of specific mutations;
  • Vaccination strategies—strengths and limitations;
  • Future strategies;
  • Role of modulators, such as the co-presence of other microbes.

Dr. Rajesh Pandey
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Vaccines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • vaccination
  • viruses
  • genomics
  • variants
  • disease

Published Papers

There is no accepted submissions to this special issue at this moment.
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