Recent Advances in Dialysis and Kidney Transplantation

A special issue of Transplantology (ISSN 2673-3943).

Deadline for manuscript submissions: closed (15 September 2023) | Viewed by 1597

Special Issue Editors


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Guest Editor
Department of General Surgery, Ospedali Riuniti Marche Nord, Pesaro, Italy
Interests: abdominal organ transplantation; transplant immunology; use of machine perfusion in kidney transplantation
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Guest Editor
Department of Urology, Division of Transplant Surgery, Miami Transplant Institute-Jackson Memorial Hospital, Miami, FL, USA
Interests: kidney and pancreas transplantation; living donor kidney transplantation; transplant immunology; xeno-transplantation; new surgical techniques in kidney transplantation
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Surgery, Division of HPB and Transplant Surgery, Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy
Interests: liver and kidney transplantation; living donor liver transplantation; hepato-pancreato-biliary surgery; ALPPS
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Kidney transplantation is universally considered the treatment of choice for end-stage renal disease. In the last two decades, important advances in surgical care and immunosuppressive therapy have led to a significant reduction in peri-operative morbidity and mortality as well as cell-mediated rejection rates, with graft and patient survival of approximately 90% and 80% at 1 and 5 years, respectively.

Concurrently, considerable improvements in the therapeutic management of chronic kidney disease-associated conditions, such as anemia and secondary hyperparathyroidism together with optimized diabetes control and the enhanced physical conditioning of patients receiving dialysis, have led to promising results and noteworthy benefits in this class of patients.

Interesting and promising research areas such as wearable and bio-artificial kidneys, kidney organoid technologies, kidney-on-a-chip, xeno-transplantation, and immune-tolerance protocols for kidney transplants recipients will substantially advance the quality of life of patients on dialysis and improve long-term outcomes for those transplanted. 

Other approaches that have been successfully adopted for many years with demonstrated important benefits have recently undergone relevant improvements, i.e., optimizing perfusate through adding peculiar substances during hypothermic machine perfusion or applying regenerative therapies in normothermic machine perfusion.

The present Special Issue intends to explore the most recent progress regarding the areas of dialysis and kidney transplantation. Both clinical and technological evolutions will be considered with the option of including narrative reviews, meta-analysis, and case reports of particular interest or exceptional didactical value.

“Recent Advances in Dialysis and Kidney Transplantation” will give specialists involved in the care of end-stage renal patients and renal transplant recipients the opportunity to share their experience or point of view on several relevant topics with the primary aim of improving global knowledge and patient outcomes.

You may choose our Joint Special Issue in Medicina.   

Dr. Paolo Vincenzi
Prof. Dr. Gaetano Ciancio
Prof. Dr. Marco Vivarelli
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Transplantology is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • kidney transplantation
  • dialysis
  • robotic surgery
  • machine perfusion
  • kidney-on-a-chip
  • kidney organoid
  • bioartificial kidney
  • xeno-transplantation
  • immune tolerance

Published Papers (1 paper)

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Research

13 pages, 707 KiB  
Article
Lower Extremity Peripheral Arterial Disease and Its Relationship with Adverse Outcomes in Kidney Transplant Recipients: A Retrospective Cohort Study
by Luis Carlos Alvarez-Perdomo, John Ubeimar Cataño-Bedoya, Maribel Plaza-Tenorio, Ana María Botero-Mora, Isabel del Pilar Cardozo-Moreno, Luis Manuel Barrera-Lozano, Jaime Alberto Ramírez-Arbeláez and Carlos M. Ardila
Transplantology 2023, 4(3), 111-123; https://doi.org/10.3390/transplantology4030012 - 14 Jul 2023
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Abstract
The purpose of the study was to characterize lower extremity peripheral arterial disease (LEPAD) in a series of kidney transplant patients and to assess the impact on adverse outcomes. A retrospective cohort study was conducted including kidney transplant recipient patients who underwent screening [...] Read more.
The purpose of the study was to characterize lower extremity peripheral arterial disease (LEPAD) in a series of kidney transplant patients and to assess the impact on adverse outcomes. A retrospective cohort study was conducted including kidney transplant recipient patients who underwent screening for LEPAD. The outcomes evaluated were classified as perioperative and post-transplant, including cardiovascular events, amputation, mortality, and loss of the graft. A total of 141 renal transplant patients screened for LEPAD were identified, with an average follow-up of 3 years. LEPAD occurred in 14.2% (20/141). No differences in cardiovascular risk factors were found between the groups, except for smoking (45% vs. 24%, p < 0.05). In the group with LEPAD, the most compromised anatomical segment was the infrapopliteus, with no iliac involvement found. The Cox proportional hazards model indicated that the variables age, gender, and weight were significant in patients with LEPAD. There were no differences between the groups in terms of graft loss and death. The infrapopliteal segment is the area of greatest stenosis in kidney transplant patients with LEPAD. Together with smoking, they can explain the presence of major amputations in kidney transplant patients; however, they had no impact on graft functionality or death. Full article
(This article belongs to the Special Issue Recent Advances in Dialysis and Kidney Transplantation)
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