Dear Colleagues,

Kidney transplantation is universally considered the treatment of choice for end-stage renal disease. In the last two decades, important advances in surgical care and immunosuppressive therapy have led to a significant reduction in peri-operative morbidity and mortality as well as cell-mediated rejection rates, with graft and patient survival of approximately 90% and 80% at 1 and 5 years, respectively.

Concurrently, considerable improvements in the therapeutic management of chronic kidney disease-associated conditions, such as anemia and secondary hyperparathyroidism together with optimized diabetes control and the enhanced physical conditioning of patients receiving dialysis, have led to promising results and noteworthy benefits in this class of patients.

Interesting and promising research areas such as wearable and bio-artificial kidneys, kidney organoid technologies, kidney-on-a-chip, xeno-transplantation, and immune-tolerance protocols for kidney transplants recipients will substantially advance the quality of life of patients on dialysis and improve long-term outcomes for those transplanted. 

Other approaches that have been successfully adopted for many years with demonstrated important benefits have recently undergone relevant improvements, i.e., optimizing perfusate through adding peculiar substances during hypothermic machine perfusion or applying regenerative therapies in normothermic machine perfusion.

The present Special Issue intends to explore the most recent progress regarding the areas of dialysis and kidney transplantation. Both clinical and technological evolutions will be considered with the option of including narrative reviews, meta-analysis, and case reports of particular interest or exceptional didactical value.

“Recent Advances in Dialysis and Kidney Transplantation” will give specialists involved in the care of end-stage renal patients and renal transplant recipients the opportunity to share their experience or point of view on several relevant topics with the primary aim of improving global knowledge and patient outcomes.

You may choose our Joint Special Issue in Medicina.   

Dr. Paolo Vincenzi
Prof. Dr. Gaetano Ciancio
Prof. Dr. Marco Vivarelli
Guest Editors

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• kidney transplantation
• dialysis
• robotic surgery
• machine perfusion
• kidney-on-a-chip
• kidney organoid
• bioartificial kidney
• xeno-transplantation
• immune tolerance