Special Issue "Interactions across Different Exposures and Life-Stages in Exposome Research"
Deadline for manuscript submissions: closed (20 May 2022) | Viewed by 6527
Interests: biomarkers; environmental genomics; DNA damage and repair; environmental toxicology; cancer epidemiology
Interests: human exposome; environmental health; non-pharmacological trial; metabolomics
The concept of the exposome has broadened the range of exposures that must be considered for their possible role in the pathogenesis of human disease and has highlighted the importance of the effects that such exposures, occurring at different life-stages, exert in the determination of the overall risk of disease. An additional major consideration highlighted by the exposome concept concerns the way in which different exposures, whether concurrent or occurring at different life-stages, may interact and jointly modify the overall risk of disease.
Thanks to these innovative ideas, the exposome has served as a stimulus for significant advances in various areas of public and environmental health research, including exposure assessment, in utero and early-life exposures and downstream effects, as well as novel statistical tools for the analysis of highly complex datasets. On the other hand, the problem of potential interactions between the multiplicity of exposures has been less extensively studied and still represents a largely unexplored practical and theoretical challenge. The identification of such interactions in the complexity of exposures or co-exposures, often highly correlated, that are often present in high-dimensional datasets of population health, warrants the use of specialized study designs and advanced algorithms for statistical analyses. Environment-wide association studies and their exposomic tools represent novel approaches to tackle societal challenges in environmental health, toxicology, and precision medicine. For this Special Issue, we wish to invite manuscripts of all types (original studies, reviews, perspectives, etc.) that address all of the above aspects and the utility of the exposome’s methodological framework, with a particular focus on the interactions between exposures and across different life-stages.
Prof. Dr. Soterios A. Kyrtopoulos
Dr. Konstantinos C. Makris
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Toxics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- mixture toxicology
- in utero exposures
- epigenetic memory
- delayed effects
- early-life exposures
- nutrient deficiencies
- social stress
- environment-wide association studies
- acquired susceptibility