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Sinusitis
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Feature Papers in Sinusitis 2021
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Feature Papers in Sinusitis 2021

A special issue of Sinusitis (ISSN 2673-351X).

Deadline for manuscript submissions: closed (31 December 2021) | Viewed by 18924

Special Issue Editor

Dr. Eleonora Nucera

E-Mail Website
Guest Editor
Allergy Unit, Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Largo F. Vito, 1, 00168 Rome, Italy
Interests: diagnosis and therapy of respiratory allergy; diagnosis and treatment of food allergies/intolerances; diagnosis and therapy of latex allergy; diagnosis and treatment of allergies/intolerances to drugs; diagnosis and treatment of insect venom allergy; diagnosis and treatment of nickel allergy; diagnosis and treatment of contact allergies; diagnosis and therapy of chronic urticaria; medical therapy of nasal polyps
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear colleagues,

We are pleased to announce a Special Issue entitled “Feature Paper in Sinusitis 2021”. Sinusitis is an international, peer-reviewed, open access journal, which provides an advanced forum for studies on all aspects of rhinology. The journal will join other successful international journals in the field of rhinology, with the aim of promoting knowledge and important new findings. Though this is a young, new journal, we expect it to experience rapid and exponential growth, as other new journals have achieved in the MDPI platform.

In this Special Issue, we are inviting manuscripts from all sinusitis fields considered to be of interest to our international readers. In this case, well-designed studies and good datasets are required to promote the quality of, and interest in, our new journal. We welcome both original research articles and comprehensive review papers. Papers in this Special Issue will be published via our open access platform after a thorough peer review, a process which will benefit both our authors and readers.

You are welcome to send short proposals for feature paper submissions to the Editorial Office (sinusitis@mdpi.com) before submission.

Dr. Eleonora Nucera
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sinusitis is an international peer-reviewed open access semiannually journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Prevention, diagnosis, and management of rhinosinusitis
  • Sinusitis causes
  • Chronic and acute sinusitis
  • Sinusitis related to tumors, smoking, cystic fibrosis, systemic diseases
  • Sinusitis complications
  • Pathophysiology and pathogenesis of sinusitis and asthma
  • Epidemiological studies on rhinosinusitis and asthma
  • Molecular genetics in sinusitis
  • Pharmacology in sinusitis
  • Clinical symptoms and therapeutics
  • New diagnostic tools and techniques
  • Viral, fungal, and bacterial infections
  • Veterinary sciences.

Published Papers (3 papers)

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Research

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11 pages, 445 KiB  
Article
Persistent Nasal Obstruction: An Expression of the Pro-Inflammatory State?
by Fernando M. Calatayud-Sáez, Blanca Calatayud and Ana Calatayud
Sinusitis 2021, 5(1), 90-100; https://doi.org/10.3390/sinusitis5010010 - 15 Jun 2021
Cited by 5 | Viewed by 4278
Abstract
Introduction: During the first years of life, the oro-pharyngeal lymphoid tissue gradually increases in size, causing in some children difficulty breathing and often leading to surgical removal of the tonsils and adenoids. The objective of the study is to assess the effects of [...] Read more.
Introduction: During the first years of life, the oro-pharyngeal lymphoid tissue gradually increases in size, causing in some children difficulty breathing and often leading to surgical removal of the tonsils and adenoids. The objective of the study is to assess the effects of the Mediterranean diet in children who had chronic upper airway obstruction. Material and methods: This was a prospective study pre-test/post-test comparison. Eighty-seven patients from two to eight years old were recruited. A food reeducation program based on the Mediterranean diet was applied for one year. Clinical, therapeutic, and anthropometric variables were studied. Results: The degree of nasal obstruction decreased in 95.1% of the patients. After the nutritional intervention, the number of colds with bacterial complications decreased by 80.26%; 60.9% had no bacterial complications during the year of the study. The use of antibiotics decreased by 81.94%. Symptomatic treatment decreased by 61.2%. Most patients did not require surgical intervention, and clinical evolution suggested that it would no longer be necessary. Conclusions: We can conclude by saying that the application of the traditional Mediterranean diet could be effective in the prevention and treatment of persistent nasal obstruction, limiting pharmacological and surgical intervention in many of these patients. Full article
(This article belongs to the Special Issue Feature Papers in Sinusitis 2021)
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Review

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19 pages, 2654 KiB  
Review
A Review on the Medicinal and Pharmacological Properties of Traditional Ethnomedicinal Plant Sonapatha, Oroxylum indicum
by Ganesh Chandra Jagetia
Sinusitis 2021, 5(1), 71-89; https://doi.org/10.3390/sinusitis5010009 - 25 May 2021
Cited by 12 | Viewed by 9830
Abstract
Oroxylum indicum, Sonapatha is traditionally used to treat asthma, biliousness, bronchitis, diarrhea, dysentery, fevers, vomiting, inflammation, leukoderma, skin diseases, rheumatoid arthritis, wound injury, and deworm intestine. This review has been written by collecting the relevant information from published material on various ethnomedicinal and [...] Read more.
Oroxylum indicum, Sonapatha is traditionally used to treat asthma, biliousness, bronchitis, diarrhea, dysentery, fevers, vomiting, inflammation, leukoderma, skin diseases, rheumatoid arthritis, wound injury, and deworm intestine. This review has been written by collecting the relevant information from published material on various ethnomedicinal and pharmacological aspects of Sonapatha by making an internet, PubMed, SciFinder, Science direct, and Google Scholar search. Various experimental studies have shown that Sonapatha scavenges different free radicals and possesses alkaloids, flavonoids, cardio glycosides, tannins, sterols, phenols, saponins, and other phytochemicals. Numerous active principles including oroxylin A, chrysin, scutellarin, baicalein, and many more have been isolated from the different parts of Sonapatha. Sonapatha acts against microbial infection, cancer, hepatic, gastrointestinal, cardiac, and diabetic disorders. It is useful in the treatment of obesity and wound healing in in vitro and in vivo preclinical models. Sonapatha elevates glutathione, glutathione-s-transferase, glutathione peroxidase, catalase, and superoxide dismutase levels and reduces aspartate transaminase alanine aminotransaminase, alkaline phosphatase, lactate dehydrogenase, and lipid peroxidation levels in various tissues. Sonapatha activates the expression of p53, pRb, Fas, FasL, IL-12, and caspases and inhibited nuclear factor kappa (NF-κB), cyclooxygenase (COX-2), tumor necrosis factor (TNFα), interleukin (IL6), P38 activated mitogen-activated protein kinases (MAPK), fatty acid synthetase (FAS), sterol regulatory element-binding proteins 1c (SREBP-1c), proliferator-activated receptor γ2 (PPARγ2), glucose transporter (GLUT4), leptin, and HPV18 oncoproteins E6 and E7 at the molecular level, which may be responsible for its medicinal properties. The phytoconstituents of Sonapatha including oroxylin A, chrysin, and baicalein inhibit the replication of SARS-CoV-2 (COVID-19) in in vitro and in vivo experimental models, indicating its potential to contain COVID-19 infection in humans. The experimental studies in various preclinical models validate the use of Sonapatha in ethnomedicine and Ayurveda. Full article
(This article belongs to the Special Issue Feature Papers in Sinusitis 2021)
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Other

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9 pages, 2679 KiB  
Case Report
Clearance of Bone Substitute in Gel Form Accidentally Dispersed into the Sinus Cavity during Transcrestal Maxillary Sinus Floor Elevation: Two-Case Report
by Fabio Bernardello, Teresa Lombardi and Claudio Stacchi
Sinusitis 2021, 5(2), 132-140; https://doi.org/10.3390/sinusitis5020014 - 27 Oct 2021
Cited by 1 | Viewed by 3975
Abstract
Sinus membrane perforation is the most frequent intraoperative complication occurring during maxillary sinus floor elevation. Although numerous techniques for perforation management are present, grafting material dissemination may still occur, representing a potential trigger factor leading to acute or chronic sinusitis. This case report [...] Read more.
Sinus membrane perforation is the most frequent intraoperative complication occurring during maxillary sinus floor elevation. Although numerous techniques for perforation management are present, grafting material dissemination may still occur, representing a potential trigger factor leading to acute or chronic sinusitis. This case report describes two cases of xenogeneic bone substitute in gel form accidentally dispersed into the sinus cavity during maxillary sinus floor elevation with a transcrestal approach. In both cases, immediately postoperative radiographic imaging showed an important amount of gel graft dislodged into the sinus cavity as a consequence of hidden perforations that remained undetected during surgery. Patients were monitored for 6 months after surgery and reported no signs or symptoms related to possible sinus disease. Control radiographs showed no sinus membrane hypertrophy and/or presence of residual disseminated gel, confirming complete clearance of the accidentally dispersed graft through the ostiomeatal complex. In order to minimize postoperative complications, bone substitutes in gel form could represent an interesting alternative to granular grafts for their easier clearance from the maxillary sinus cavity in case of accidental dissemination during sinus augmentation procedures. Full article
(This article belongs to the Special Issue Feature Papers in Sinusitis 2021)
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