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Optical Sensors Based on Random Laser

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Optical Sensors".

Deadline for manuscript submissions: closed (31 October 2021) | Viewed by 4854

Special Issue Editors


E-Mail Website
Guest Editor
Physics and Astronomy Department and LENS, University of Florence, 50019 Florence, Italy
Interests: optical sensors; random laser; optical pulse propagation; VUV spectroscopy; coherent control
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Physics and Astronomy Department, University of Florence, 50019 Florence, Italy
Interests: optical sensors; random laser; optical pulse propagation; light propagation through biological tissues and diffusive media
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Physics and Astronomy Department, University of Florence, 50019 Florence, Italy
Interests: optical sensors; random laser; light propagation through biological tissues and diffusive media; tissues spectroscopy; diffuse optical imaging; Raman diffuse spectroscopy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Random lasing is a physical phenomenon that is responsible for the generation of a special kind of optical radiation with mixed properties of common light and laser. In a random laser system, the last of the three elements that allow the radiation to persist inside the gain medium for the sufficiently long time required for amplification is missing. Scattering, due to disorder of the material, is the mechanism that increases the radiation lifetime, allowing the stimulated emission to prevail.

Besides the basic interest for studying random lasing, such as the statistical issue of the emission behavior, such an optical source has recently been proposed as a useful and very promising tool for developing optical sensors in several fields, such as biological and medical diagnostics research, earth sciences, optical fiber sensing engineering, and industrial quality control as well as for developing new kind of photonic devices.

Prof. Stefano Cavalieri
Dr. Federico Tommasi
Dr. Fabrizio Martelli
Guest Editors

Manuscript Submission Information

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Keywords

  • optical sensor
  • random laser
  • optical diagnostics
  • photonic disorder
  • random fiber
  • laser spectroscopy

Published Papers (2 papers)

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Research

10 pages, 965 KiB  
Communication
Direct Measurement of the Reduced Scattering Coefficient by a Calibrated Random Laser Sensor
by Federico Tommasi, Baptiste Auvity, Lorenzo Fini, Fabrizio Martelli and Stefano Cavalieri
Sensors 2022, 22(4), 1401; https://doi.org/10.3390/s22041401 - 11 Feb 2022
Cited by 2 | Viewed by 1649
Abstract
The research in optical sensors has been largely encouraged by the demand for low-cost and less or non-invasive new detection strategies. The invention of the random laser has opened a new frontier in optics, providing also the opportunity to explore new possibilities in [...] Read more.
The research in optical sensors has been largely encouraged by the demand for low-cost and less or non-invasive new detection strategies. The invention of the random laser has opened a new frontier in optics, providing also the opportunity to explore new possibilities in the field of sensing, besides several different and peculiar phenomena. The main advantage in exploiting the physical principle of the random laser in optical sensors is due to the presence of the stimulated emission mechanism, which allows amplification and spectral modification of the signal. Here, we present a step forward in the exploitation of this optical phenomenon by a revisitation of a previous experimental setup, as well as the measurement method, in particular to mitigate the instability of the results due to shot-to-shot pump energy fluctuations. In particular, the main novelties of the setup are the use of optical fibers, a reference sensor, and a peristaltic pump. These improvements are devoted to: eliminating optical beam alignment issues; improving portability; mitigating the variation in pump energy and gain medium performances over time; realizing an easy and rapid change of the sensed medium. The results showed that such a setup can be considered a prototype for a portable device for directly measuring the scattering of liquid samples, without resorting to complicated numerical or analytic inversion procedures of the measured data, once the suitable calibration of the system is performed. Full article
(This article belongs to the Special Issue Optical Sensors Based on Random Laser)
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11 pages, 2509 KiB  
Article
Random Lasing Detection of Mutant Huntingtin Expression in Cells
by Sergio de Armas-Rillo, Felipe Fumagallo-Reading, Diego Luis-Ravelo, Beatriz Abdul-Jalbar, Tomás González-Hernández and Fernando Lahoz
Sensors 2021, 21(11), 3825; https://doi.org/10.3390/s21113825 - 31 May 2021
Cited by 7 | Viewed by 2203
Abstract
Huntington’s disease (HD) is an autosomal dominant, incurable neurodegenerative disease caused by mutation in the huntingtin gene (HTT). HTT mutation leads to protein misfolding and aggregation, which affect cells’ functions and structural features. Because these changes might modify the scattering strength [...] Read more.
Huntington’s disease (HD) is an autosomal dominant, incurable neurodegenerative disease caused by mutation in the huntingtin gene (HTT). HTT mutation leads to protein misfolding and aggregation, which affect cells’ functions and structural features. Because these changes might modify the scattering strength of affected cells, we propose that random lasing (RL) is an appropriate technique for detecting cells that express mutated HTT. To explore this hypothesis, we used a cell model of HD based on the expression of two different forms—pathogenic and non-pathogenic—of HTT. The RL signals from both cell profiles were compared. A multivariate statistical analysis of the RL signals based on the principal component analysis (PCA) and linear discriminant analysis (LDA) techniques revealed substantial differences between cells that expressed the pathogenic and the non-pathogenic forms of HTT. Full article
(This article belongs to the Special Issue Optical Sensors Based on Random Laser)
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