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Molecular Imaging and Sensing: Design, Development, and Applications

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Sensing and Imaging".

Deadline for manuscript submissions: closed (20 July 2023) | Viewed by 2503

Special Issue Editor


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Guest Editor
Independent Researcher, Newcastle upon Tyne NE4 5BX, UK
Interests: molecular imaging; chemosensors
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The design and development of molecular imaging probes are related to the novel biomarkers that will help and improve the early diagnosis and staging of several deadly diseases, including cancer. Significantly, the sensor or responsive units that selectively recognize the molecule of interest in deep tissue incorporated imaging probes often provide invaluable information about the disease progression and stages. 
Therefore, this Special Issue is addressed in the design, development, and applications of sensors or responsive unit(s)-incorporated molecular imaging probes.

Dr. Sellamuthu Anbu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • molecular imaging
  • fluorophores
  • responsive magnetic resonance imaging probes
  • theranostics
  • cancer imaging
  • overexpressing targets in diseased tissue

Published Papers (1 paper)

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Review

20 pages, 2433 KiB  
Review
Trends in Single-Molecule Total Internal Reflection Fluorescence Imaging and Their Biological Applications with Lab-on-a-Chip Technology
by Louis Colson, Youngeun Kwon, Soobin Nam, Avinashi Bhandari, Nolberto Martinez Maya, Ying Lu and Yongmin Cho
Sensors 2023, 23(18), 7691; https://doi.org/10.3390/s23187691 - 06 Sep 2023
Cited by 5 | Viewed by 1982
Abstract
Single-molecule imaging technologies, especially those based on fluorescence, have been developed to probe both the equilibrium and dynamic properties of biomolecules at the single-molecular and quantitative levels. In this review, we provide an overview of the state-of-the-art advancements in single-molecule fluorescence imaging techniques. [...] Read more.
Single-molecule imaging technologies, especially those based on fluorescence, have been developed to probe both the equilibrium and dynamic properties of biomolecules at the single-molecular and quantitative levels. In this review, we provide an overview of the state-of-the-art advancements in single-molecule fluorescence imaging techniques. We systematically explore the advanced implementations of in vitro single-molecule imaging techniques using total internal reflection fluorescence (TIRF) microscopy, which is widely accessible. This includes discussions on sample preparation, passivation techniques, data collection and analysis, and biological applications. Furthermore, we delve into the compatibility of microfluidic technology for single-molecule fluorescence imaging, highlighting its potential benefits and challenges. Finally, we summarize the current challenges and prospects of fluorescence-based single-molecule imaging techniques, paving the way for further advancements in this rapidly evolving field. Full article
(This article belongs to the Special Issue Molecular Imaging and Sensing: Design, Development, and Applications)
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