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Development and Validation of Biophotonic Sensors towards Research, Industrial and Clinical Applications

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Optical Sensors".

Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 196

Special Issue Editor

Special Issue Information

Dear Colleagues,

There has been a growing interest in biophotonic sensors in applications including biomedicine, the environment, forensics, livestock, agriculture, quality control and validation in food, pharmaceutical and cosmetic industries, military, security, and a wide range of other applications. Emerging biophotonic sensors have been developed to enable the non-invasive observation of biological systems with high sensitivity, accuracy, and spatial and temporal resolutions. These biological systems include organisms, tissues, biofluids, cells and subcellular structures.

In particular, optical and photonic technologies enable simultaneous sensing at structural and molecular levels, which is attractive for numerous devices, including (1) compact devices for cameras/imaging sensors, smartphones, wearable sensors, (2) high-precision sensors for quality control, (3) high-sensitive/high-contrast sensors to unveil biological processes happening at small analyte concentrations, (4) high-resolution sensors to observe structures at nano- and micro-scales, (5) long-distance sensors to monitor organisms without perturbing the ecosystem or for real-time online analysis of biological systems in industrial products or bioreactors.

This Special Issue focuses on the development and validation of novel biophotonic sensors for their targeted applications, and advances in optical techniques for next-generation devices. Contributions are invited for this Special Issue from researchers working on hardware and software development of biophotonic sensors.

Biophotonic sensors include imaging devices, point-spectroscopy instruments and fiber optic devices, as well as sensors based on micro- and nano-photonics, waveguide devices and novel materials. Optical techniques include 2D or 3D imaging and spectroscopy at reflectance, transmittance, confocal, and near-field geometries, as well as probing from the ultraviolet region through the visible (UV-Vis) and infrared region (IR) to the terahertz (THz) region. These techniques include, but are not limited to, photoacoustic and acousto-optic tomography or topography, OCT, CARS, SRS, SERS, TERS, SHG, and can explore photophysical processes, such as light absorption, scattering, fluorescence, multi-photon absorption, second-harmonic generation, Raman, and upconversion.

Topics of interest include, but are not limited to, the following:

  • Validation of existing sources, light-shaping devices, detectors and data processing approaches for novel applications.
  • Optimization of novel or existing software for real-time, high accuracy and/or high-throughput sample analysis.
  • Investigation of new biomarkers, imaging and spectroscopy features and applications.
  • Development and performance of new detectors.
  • Development and performance of new sources and light-shaping devices.
  • Development and performance of novel 2D or 3D imaging sensing systems.
  • Development and performance of lab-on-a-chip devices.
  • Development and performance of novel computational imaging approaches, including compressive sensing and machine/deep learning techniques.

Dr. Marcelo Saito Nogueira
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • sensor technology and application
  • biosensors
  • physical sensors
  • signal/data processing
  • machine/deep learning
  • lab-on-a-chip
  • waveguides
  • approaches for technology standardization and validation
  • non-/minimally invasive, non-destructive technologies
  • automated, and/or real-time techniques
  • imaging, tomography, topography and/or spectroscopy
  • endoscopy, microscopy, and/or gas spectroscopy
  • analysis of biological tissue, body gases (breath analysis) and fluids (biofluids) and/or biosolids
  • screening, diagnostics, theranostics and/or dosimetry applications
  • diagnostic and prognostic biomarkers
  • time-resolved (or time-domain) techniques
  • spatially resolved techniques frequency-domain techniques
  • multi-photon techniques
  • upconverting nanoparticles
  • second harmonic generation
  • diffuse reflectance spectroscopy
  • elastic scattering spectroscopy
  • fluorescence spectroscopy
  • vibrational spectroscopy
  • ftir spectroscopy
  • raman spectroscopy
  • optical coherence tomography

Published Papers

There is no accepted submissions to this special issue at this moment.
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