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Editorial Board Members’ Collection Series: Immunosensors

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 2881

Special Issue Editors


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Guest Editor
1. Department of Neuroscience, Central Clinical School, Monash University, Melbourne, Australia
2. Department of Medicine, University of Melbourne, Melbourne, Australia
Interests: immunosensor; epilepsy; drugs; point-of-care test; pharmacogenetics; genetics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Recent developments in the field of immunosensors related to the addition of nanomaterials for increased sensitivity, multiplexing or microfluidic devices can provide promising uses in industry and clinical trials. The main areas of application, along with biomedical analysis, are drug abuse control, food testing, and environmental analysis. Recently, new green approaches have been applied in this field, such as the use of recycled or no wasted materials.

The aim of this Special Issue is to provide an opportunity for researchers to publish their new ideas and latest research related to advanced immunosensor technology with electrochemical detection.

Dr. Laura Micheli
Prof. Dr. Patrick Kwan
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • immunoassay
  • biosensor
  • nanomaterials
  • screen-printed electrodes
  • green approach

Published Papers (2 papers)

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Research

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13 pages, 4713 KiB  
Article
Surface Acoustic Wave Immunosensor for Detection of Botulinum Neurotoxin
by Michał Grabka, Krzysztof Jasek and Zygfryd Witkiewicz
Sensors 2023, 23(18), 7688; https://doi.org/10.3390/s23187688 - 6 Sep 2023
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Abstract
A Love-type acoustic wave sensor (AT-cut quartz substrate, SiO2 guiding layer) with a center frequency of approximately 120 MHz was used to detect a simulant of pathogenic botulinum neurotoxin type A—recombinant of BoNT-A light chain—in liquid samples. The sensor was prepared by [...] Read more.
A Love-type acoustic wave sensor (AT-cut quartz substrate, SiO2 guiding layer) with a center frequency of approximately 120 MHz was used to detect a simulant of pathogenic botulinum neurotoxin type A—recombinant of BoNT-A light chain—in liquid samples. The sensor was prepared by immobilizing monoclonal antibodies specific for botulinum neurotoxin via a thiol monolayer deposited on a gold substrate. Studies have shown that the sensor enables selective analyte detection within a few minutes. In addition, the sensor can be used several times (regeneration of the sensor is possible using a low pH buffer). Nevertheless, the detectability of the analyte is relatively low compared to other analytical techniques that can be used for rapid detection of botulinum neurotoxin. The obtained results confirm the operation of the proposed sensor and give hope for further development of this label-free technique for detecting botulinum neurotoxin. Full article
(This article belongs to the Special Issue Editorial Board Members’ Collection Series: Immunosensors)
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Review

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16 pages, 1242 KiB  
Review
Immunosensors for Autoimmune-Disease-Related Biomarkers: A Literature Review
by Chrysoula-Evangelia Karachaliou and Evangelia Livaniou
Sensors 2023, 23(15), 6770; https://doi.org/10.3390/s23156770 - 28 Jul 2023
Cited by 2 | Viewed by 1639
Abstract
Immunosensors are a special class of biosensors that employ specific antibodies for biorecognition of the target analyte. Immunosensors that target disease biomarkers may be exploited as tools for disease diagnosis and/or follow-up, offering several advantages over conventional analytical techniques, such as rapid and [...] Read more.
Immunosensors are a special class of biosensors that employ specific antibodies for biorecognition of the target analyte. Immunosensors that target disease biomarkers may be exploited as tools for disease diagnosis and/or follow-up, offering several advantages over conventional analytical techniques, such as rapid and easy analysis of patients’ samples at the point-of-care. Autoimmune diseases have been increasingly prevalent worldwide in recent years, while the COVID-19 pandemic has also been associated with autoimmunity. Consequently, demand for tools enabling the early and reliable diagnosis of autoimmune diseases is expected to increase in the near future. To this end, interest in immunosensors targeting autoimmune disease biomarkers, mainly, various autoantibodies and specific pro-inflammatory proteins (e.g., specific cytokines), has been rekindled. This review article presents most of the immunosensors proposed to date as potential tools for the diagnosis of various autoimmune diseases, such as type 1 diabetes, rheumatoid arthritis, and multiple sclerosis. The signal transduction and the immunoassay principles of each immunosensor have been suitably classified and are briefly presented along with certain sensor elements, e.g., special nano-sized materials used in the construction of the immunosensing surface. The main concluding remarks are presented and future perspectives of the field are also briefly discussed. Full article
(This article belongs to the Special Issue Editorial Board Members’ Collection Series: Immunosensors)
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