Special Issue "Nuclear Receptors: Honorary Special Issue Commemorating the Work of Prof. Jan-Åke Gustafsson"
A special issue of Receptors (ISSN 2813-2564).
Deadline for manuscript submissions: closed (30 April 2023) | Viewed by 4669
Recently, we passed 25-year mark since the discovery of the two important nuclear receptors LXRβ and Erβ. The publication of Professor Gustafsson’s paper (PNAS 14;92 (6) 2096-2100, 1995) where he described the cloning of the nuclear receptor OR-1, later renamed to LXRβ, was fundamental to understanding cholesterol homeostasis and its regulation, and has resulted in many publications from Professor Gustafsson and others. One year later, another nuclear receptor was cloned (PNAS 93 (12) 5925-5930, 1996). This was a second estrogen receptor and was named Erβ; it was a fundamental paradigm shift since all effects until then had been attributed to the only known estrogen receptor which was then renamed to ERα. The cloning of ERβ initiated much activity from individual researchers as well as from companies because of the potential new drug target for the treatment of diseases. Evaluation of ERβ as a drug target is still ongoing. In addition, Gustafsson has been involved in revealing the 3D structure of nuclear receptors, the binding of nuclear receptors to DNA, and the discovery of the steroid response element.
This Special Issue is focused on the role of nuclear receptors in health and disease. The Special Issue begins with a short review of Professor Gustafsson’s contribution to the field of nuclear receptors followed by original research articles and reviews on all aspects of nuclear receptors in health and disease.
Dr. Anders Strom
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Receptors is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- estrogen receptor beta
- liver X receptor beta
- nuclear receptors
- steroid hormones