Tissue and Immunological Features of the Human/Prosthesis Interface

A special issue of Prosthesis (ISSN 2673-1592).

Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 16168

Special Issue Editor


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Guest Editor

Special Issue Information

Dear Colleagues,

The new biomaterials have made a lot of progress in recent years. The basic characteristics of biomaterials must be biocompatibility with the human organism. On the basis of the chemical and physical characteristics of the materials, a different reaction is expected from the body. Some biomechanical characteristics can influence a different response from tissues and the body, and especially in the case of prostheses that require a biological seal, immunological reactions are also expected from the host. Which can lead to inflammatory processes and cause rejection of the prosthesis. The purpose of this special issue is to evaluate all tissue and immunological characteristics of the organism, with respect to prostheses on different parts of the body.

Prof. Dr. Marco Cicciu
Guest Editor

Manuscript Submission Information

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Keywords

  • Cytokines
  • Inflammation
  • Immunological
  • Biomechanics
  • Prosthesis
  • Prosthesis Features
  • Biocompatibility

Published Papers (4 papers)

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Research

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16 pages, 2577 KiB  
Article
A Parametric Study on a Dental Implant Geometry Influence on Bone Remodelling through a Numerical Algorithm
by Dario Santonocito, Fabiana Nicita and Giacomo Risitano
Prosthesis 2021, 3(2), 157-172; https://doi.org/10.3390/prosthesis3020016 - 04 Jun 2021
Cited by 11 | Viewed by 3498
Abstract
To ensure the long-term success of a dental implant, it is imperative to understand how chewing loads are transferred through the implant prosthetic components to the surrounding bone tissue. The stress distribution depends on several factors, such as load type, bone–implant interface, shape [...] Read more.
To ensure the long-term success of a dental implant, it is imperative to understand how chewing loads are transferred through the implant prosthetic components to the surrounding bone tissue. The stress distribution depends on several factors, such as load type, bone–implant interface, shape and materials of the fixture and quality and quantity of the bone. These aspects are of fundamental importance to ensure implant stability and to evaluate the remodelling capacity of the bone tissue to adapt to its biomechanical environment. A bone remodelling algorithm was formulated by the authors and implemented by means of finite element simulations on four different implants with several design characteristics. Internal bone microstructure and density, apposition/resorption of tissue and implant stability were evaluated over a period of 12 months, showing the influence of the geometry on bone tissue evolution over time. Bone remodelling algorithms may be a useful aid for clinicians to prevent possible implant failures and define an adequate implant prosthetic rehabilitation for each patient. In this work, for the first time, external bone remodelling was numerically predicted over time. Full article
(This article belongs to the Special Issue Tissue and Immunological Features of the Human/Prosthesis Interface)
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7 pages, 1994 KiB  
Article
Comparison of Two Low-Profile Prosthetic Retention System Interfaces: Preliminary Data of an In Vitro Study
by Gabriele Cervino, Marco Montanari, Dario Santonocito, Fabiana Nicita, Riccardo Baldari, Claudio De Angelis, Gianni Storni and Luca Fiorillo
Prosthesis 2019, 1(1), 54-60; https://doi.org/10.3390/prosthesis1010007 - 27 Nov 2019
Cited by 25 | Viewed by 2926
Abstract
In recent years, a major research goal of companies has been to create mechanical components suitable for rehabilitation that are safer and more reliable. Evaluating their biomechanical features could be a way to improve them. The purpose of this study was to evaluate [...] Read more.
In recent years, a major research goal of companies has been to create mechanical components suitable for rehabilitation that are safer and more reliable. Evaluating their biomechanical features could be a way to improve them. The purpose of this study was to evaluate the different biomechanical features of low-profile retentive systems (Rhein®). Two different attachment systems were tested: OT Equator® Smart Box and Locator® R-TX. Once a machine was created for the simulation of the connection and disconnection of the attacks in a combined manner, it was possible to evaluate these parameters over time. Attachments were mounted in two different configurations of the divergence angle: 10° and 50°. The drop retention force proved to be stable over time. The Locator® R-TX attachment experienced a more rapid decrement of the retention force than the OT Equator® Smart Box. Both tested systems experienced a high drop in retention; this drop tended to stabilize after 1.5 years of use, and it was correlated with the divergence angle. The OT Equator® Smart Box system underwent this loss of retention more gradually than the Locator® R-TX. This study demonstrates preliminary results from a bioengineering and biomechanical point of view, providing useful information for the continuous improvement of these devices and, therefore, for the quality of patients’ oral health. Full article
(This article belongs to the Special Issue Tissue and Immunological Features of the Human/Prosthesis Interface)
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13 pages, 7917 KiB  
Article
Prosthetic and Mechanical Parameters of the Facial Bone under the Load of Different Dental Implant Shapes: A Parametric Study
by Marco Cicciù, Gabriele Cervino, Antonella Terranova, Giacomo Risitano, Marcello Raffaele, Filippo Cucinotta, Dario Santonocito and Luca Fiorillo
Prosthesis 2019, 1(1), 41-53; https://doi.org/10.3390/prosthesis1010006 - 14 Nov 2019
Cited by 43 | Viewed by 4370
Abstract
In recent years the science of dental materials and implantology have taken many steps forward. In particular, it has tended to optimize the implant design, the implant surface, or the connection between implant and abutment. All these features have been improved or modified [...] Read more.
In recent years the science of dental materials and implantology have taken many steps forward. In particular, it has tended to optimize the implant design, the implant surface, or the connection between implant and abutment. All these features have been improved or modified to obtain a better response from the body, better biomechanics, increased bone implant contact surface, and better immunological response. The purpose of this article, carried out by a multidisciplinary team, is to evaluate and understand, through the use also of bioengineering tests, the biomechanical aspects, and those induced on the patient’s tissues, by dental implants. A comparative analysis on different dental implants of the same manufacturer was carried out to evaluate biomechanical and molecular features. Von Mises analysis has given results regarding the biomechanical behavior of these implants and above all the repercussions on the patient’s tissues. Knowing and understanding the biomechanical characteristics with studies of this type could help improve their characteristics in order to have more predictable oral rehabilitations. Full article
(This article belongs to the Special Issue Tissue and Immunological Features of the Human/Prosthesis Interface)
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14 pages, 966 KiB  
Systematic Review
Therapeutic Role of Nystatin Added to Tissue Conditioners for Treating Denture-Induced Stomatitis: A Systematic Review
by Muhammad Saad Shaikh, Ahmad Alnazzawi, Syed Rashid Habib, Mohid Abrar Lone and Muhammad Sohail Zafar
Prosthesis 2021, 3(1), 61-74; https://doi.org/10.3390/prosthesis3010007 - 03 Feb 2021
Cited by 15 | Viewed by 4355
Abstract
Denture-induced stomatitis (DIS) represents a pathological condition caused by ill-fitting dentures trauma, manifested as inflammation of the palatal tissue beneath the denture. The fungal infections are the principal contributory factors to DIS. Although the aetiology of DIS is multifactorial, the Candida albicans fungal [...] Read more.
Denture-induced stomatitis (DIS) represents a pathological condition caused by ill-fitting dentures trauma, manifested as inflammation of the palatal tissue beneath the denture. The fungal infections are the principal contributory factors to DIS. Although the aetiology of DIS is multifactorial, the Candida albicans fungal infection remains the main cause. The objective of the present systematic review was to evaluate the latest literature on the addition of nystatin into the tissue conditioners (TCs) in the management of DIS. To search the published literature about “the addition of nystatin in TCs for treating DIS”, electronic databases (PubMed (National library of medicine) and Cochrane Library (Wiley)) were searched (from 1975 until December 2020) using different keywords. Various studies described the effectiveness and efficacy of incorporating nystatin into several TCs. The present systematic review reported that the addition of nystatin is beneficial, with slight or no consequences on both the mechanical and physical features of TCs. Adding nystatin to various TCs for treating DIS can be suggested. Full article
(This article belongs to the Special Issue Tissue and Immunological Features of the Human/Prosthesis Interface)
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