Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.7
3.5
Journals
Processes
Special Issues
State of the Art of Biomaterials and Their Biomedical Applications:...
share announcement

Special Issue "State of the Art of Biomaterials and Their Biomedical Applications: From Replacement to Regeneration"

A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Biological Processes and Systems".

Deadline for manuscript submissions: closed (30 June 2023) | Viewed by 18911

Special Issue Editors

Dr. Andrea Bagno

E-Mail Website
Guest Editor
1. Department of Industrial Engineering, University of Padova, Padova, Italy
2. LifeLab. Program, Consorzio per la Ricerca Sanitaria (CORIS), Veneto Region, Italy
Interests: interactions between biomaterials and biological tissues; biomechanical characterization of native and decellularized pericardium for the production of bioprosthetic heart valves; the early detection of mechanical heart valve failure by phonocardiographic means; the assessment of skin microcirculation by laser doppler fluxmetry
Dr. Silvia Todros

E-Mail Website
Guest Editor
1. Department of Industrial Engineering, Centre for Mechanics of Biological Materials, University of Padova, via Venezia 1, 35131 Padova, Italy
2. Centre for Mechanics of Biological Materials, University of Padova, Padova, Italy
Interests: biomaterials, biomedical polymers, and biological tissues; prostheses and biomedical devices; tissue engineering; experimental characterization of physicochemical, morphological, and mechanical properties of biomaterials; computational modeling of biological tissues and structures
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Advances in biomaterial science have been always accompanied by parallel advances in biomedical and clinical applications. On the other hand, improvements in clinical applications have often required the development of innovative biomaterials: the notion of “translational medicine”, which implies transferring results from bench to bedside, is already familiar. Indeed, clinical needs have recently been moving from the “simple” replacement of damaged tissues/organs to the regeneration thereof. Thus, we have to update the traditional definition of biomaterials as “synthetic materials in contact with body fluid, which substitute/recondition a biological function of body tissue/organ”. Now, we have to start designing biomaterials able not only to “coexist” with biological tissues (safely and effectively), but also to integrate with them becoming active parts of the biological environment. In this perspective, the idea of “inert” biomaterials is obsolete! Biomaterial science can now consider a variety of approaches to create novel materials as candidates for regenerating tissues and organs, for example: biochemical functionalization of “traditional” and “novel” biomaterials; exploitation of biological tissues/organs after chemical fixation or after decellularization; and integration between biological tissues and synthetic materials. This is the way to move toward a truly personalized therapeutic approach.

This Special Issue on “State of the Art of Biomaterials and Their Biomedical Applications: From Replacement to Regeneration” aims to collect high-quality contributions that focus on the field of biomaterials for tissue/organ regeneration and their clinical applications. Topics include, but are not limited to:

  • Bioactive materials;
  • Biochemical functionalization strategies;
  • Tissue and organ decellularization;
  • Tissue and organ engineering;
  • Novel biomedical devices.

Prof. Andrea Bagno
Dr. Silvia Todros
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • bioactive materials
  • smart materials
  • medical devices
  • biocompatibility
  • tissue engineering
  • engineered tissues
  • engineered organs

Published Papers (3 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Review

get_app
Review
When the Total Hip Replacement Fails: A Review on the Stress-Shielding Effect
by
Davide Savio
and
Andrea Bagno
Processes 2022, 10(3), 612; https://doi.org/10.3390/pr10030612 - 21 Mar 2022
Cited by 22 | Viewed by 6567
Abstract
Total hip arthroplasty is one of the most common and successful orthopedic surgeries. Sometimes, periprosthetic osteolysis occurs associated with the stress-shielding effect: it results in the reduction of bone density, where the femur is not correctly loaded, and in the formation of denser [...] Read more.
Total hip arthroplasty is one of the most common and successful orthopedic surgeries. Sometimes, periprosthetic osteolysis occurs associated with the stress-shielding effect: it results in the reduction of bone density, where the femur is not correctly loaded, and in the formation of denser bone, where stresses are confined. This paper illustrates the stress shielding effect as a cause of the failing replacement of the hip joint. An extensive literature survey has been accomplished to describe the phenomenon and identify solutions. The latter refer to the design criteria and the choice of innovative materials/treatments for prosthetic device production. Experimental studies and numerical simulations have been reviewed. The paper includes an introduction to explain the scope; a section illustrating the causes of the stress shielding effect; a section focusing on recent attempts to redefine prosthetic device design criteria, current strategies to improve the osteointegration process, and a number of innovative biomaterials; functionally graded materials are presented in a dedicated section: they allow customizing prosthesis features with respect to the host bone. Conclusions recommend an integrated approach for the production of new prosthetic devices: the “engineering community” has to support the “medical community” to assure an effective translation of research results into clinical practice. Full article
(This article belongs to the Special Issue State of the Art of Biomaterials and Their Biomedical Applications: From Replacement to Regeneration)
►▼ Show Figures

Figure 1

get_app
Review
Biomaterials and Their Biomedical Applications: From Replacement to Regeneration
by
Silvia Todros
,
Martina Todesco
and
Andrea Bagno
Processes 2021, 9(11), 1949; https://doi.org/10.3390/pr9111949 - 29 Oct 2021
Cited by 29 | Viewed by 8834
Abstract
The history of biomaterials dates back to the mists of time: human beings had always used exogenous materials to facilitate wound healing and try to restore damaged tissues and organs. Nowadays, a wide variety of materials are commercially available and many others are [...] Read more.
The history of biomaterials dates back to the mists of time: human beings had always used exogenous materials to facilitate wound healing and try to restore damaged tissues and organs. Nowadays, a wide variety of materials are commercially available and many others are under investigation to both maintain and restore bodily functions. Emerging clinical needs forced the development of new biomaterials, and lately discovered biomaterials allowed for the performing of new clinical applications. The definition of biomaterials as materials specifically conceived for biomedical uses was raised when it was acknowledged that they have to possess a fundamental feature: biocompatibility. At first, biocompatibility was mainly associated with biologically inert substances; around the 1970s, bioactivity was first discovered and the definition of biomaterials was consequently extended. At present, it also includes biologically derived materials and biological tissues. The present work aims at walking across the history of biomaterials, looking towards the scientific literature published on this matter. Finally, some current applications of biomaterials are briefly depicted and their future exploitation is hypothesized. Full article
(This article belongs to the Special Issue State of the Art of Biomaterials and Their Biomedical Applications: From Replacement to Regeneration)
►▼ Show Figures

Figure 1

get_app
Review
Bladder Substitution: The Role of Tissue Engineering and Biomaterials
by
Martina Casarin
,
Alessandro Morlacco
and
Fabrizio Dal Moro
Processes 2021, 9(9), 1643; https://doi.org/10.3390/pr9091643 - 13 Sep 2021
Cited by 6 | Viewed by 2201
Abstract
Tissue engineering could play a major role in the setting of urinary diversion. Several conditions cause the functional or anatomic loss of urinary bladder, requiring reconstructive procedures on the urinary tract. Three main approaches are possible: (i) incontinent cutaneous diversion, such as ureterocutaneostomy, [...] Read more.
Tissue engineering could play a major role in the setting of urinary diversion. Several conditions cause the functional or anatomic loss of urinary bladder, requiring reconstructive procedures on the urinary tract. Three main approaches are possible: (i) incontinent cutaneous diversion, such as ureterocutaneostomy, colonic or ileal conduit, (ii) continent pouch created using different segments of the gastrointestinal system and a cutaneous stoma, and (iii) orthotopic urinary diversion with an intestinal segment with spherical configuration and anastomosis to the urethra (neobladder, orthotopic bladder substitution). However, urinary diversions are associated with numerous complications, such as mucus production, electrolyte imbalances and increased malignant transformation potential. In this context, tissue engineering would have the fundamental role of creating a suitable material for urinary diversion, avoiding the use of bowel segments, and reducing complications. Materials used for the purpose of urinary substitution are biological in case of acellular tissue matrices and naturally derived materials, or artificial in case of synthetic polymers. However, only limited success has been achieved so far. The aim of this review is to present the ideal properties of a urinary tissue engineered scaffold and to examine the results achieved so far. The most promising studies have been highlighted in order to guide the choice of scaffolds and cells type for further evolutions. Full article
(This article belongs to the Special Issue State of the Art of Biomaterials and Their Biomedical Applications: From Replacement to Regeneration)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-3
Back to TopTop