Special Issue "Isolation, Extraction and Purification of Fungal Natural Products"

A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Separation Processes".

Deadline for manuscript submissions: 29 February 2024 | Viewed by 725

Special Issue Editor

Institute of Biochemistry and Physiology of Plants and Microorganisms, Russian Academy of Sciences, Saratov, Russia
Interests: natural products chemistry; bioactive molecules; microbial fermentation; myconanotechnology; fungal biochemistry; fungal biotechnology

Special Issue Information

Dear Colleagues,

The commercial value of fungal natural products is increasing globally. The attractiveness is often related to the health-beneficial properties of bioactive compounds found in fungi. These microorganisms attract attention also as the possible participants of the plant wastes biodestruction processes known for the xylotrophic basidiomycetes, as well as the producers of unique complex of biologically active substances, frequently called mycochemicals. Significant achievements have been made in the development of fungal artificial cultivation exhibiting multiple advantages as for the processes of subsequent isolation, separation, and purification of natural products from fungi.

In recent decades, various fungal products have received great interest and seen applications in many fields, from pharmaceutics to food and agriculture. Based on the encouraging research about culinary–medicinal mushrooms, filamentous, plant endophytic fungi as a source of natural substances, a great deal of effort has been focused on discovering natural and modified fungal products for the development of functional foods and dietary supplements.

With the development of the research and application of various separation and purification techniques, the complex structure and various biological activities of fungal metabolites have been recognized. This Special Issue focuses on scientific papers dealing with various complementary studies needed to cover and enhance all of abovementioned subjects.

We encourage the submission of research or review articles focusing on the chemical composition, characteristics of biosynthesis, effect, and use of fungal natural products, both low-molecular-weight secondary metabolites of fungi and their biopolymeric compounds. Papers dealing with fungal natural products with improved biotechnological capacity through analytical, molecular, biochemical, agricultural or technological approaches, innovative uses in food and feed science are particularly welcome.

Original research articles and review articles should be focused on, but not limited to, the following topics:

(1) Isolation, separation, and purification of natural products from fungi.

(2) Characterization of the chemical composition and structural properties of the total pool of fungal metabolites.

(3) Studies of the properties, structural peculiarities, and biotechnological use of the extracellular compounds of mushrooms.

(4) Exploration of the peculiarities of biosynthesis of the mycochemicals, a structure–activity relationship for fungal products.

(5) Elucidation of the biochemical differences of fungal species by the properties of secondary metabolites spectrum leading to stress-resistance, delignifying ability, other types of vital activity.

(6) Research into fungal species capable of producing abundantly the substances of chemical groups (phenolics, indolics, terpenoids, lipidic low-molecular compounds, etc.) at the submerged cultivation.

(7) The potential applications of fungal natural products in the food, pharmaceutical, agricultural, and other areas.

Dr. Olga Tsivileva
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • natural products from fungi
  • analytical techniques application
  • chemical modifications
  • biological activity
  • structure-activity relationship
  • in vivo and in vitro studies
  • fungal products application

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:


14 pages, 1738 KiB  
Novel Stimulants of Medicinal Basidiomycetes Growth Based on Nanoparticles of N-monosubstituted Amino Acid Derivatives of Fullerene C60
Processes 2023, 11(6), 1695; https://doi.org/10.3390/pr11061695 - 01 Jun 2023
Viewed by 501
The influence of nanoparticles of hydrated C60 fullerene and its N-monoamino acid derivatives on the oxidative metabolism and growth of the mycelial biomass of basidiomycetes during their submerged cultivation was studied. It was found that the supplementation of culture media with nanoparticles [...] Read more.
The influence of nanoparticles of hydrated C60 fullerene and its N-monoamino acid derivatives on the oxidative metabolism and growth of the mycelial biomass of basidiomycetes during their submerged cultivation was studied. It was found that the supplementation of culture media with nanoparticles of the studied compounds at their final concentration range of 10−7 to 10−11 M significantly increased the resulting biomass, while the severity of the effect in this concentration range changed slightly. That prompted the use of nanomolar concentrations of compounds as reasonable. The most pronounced stimulating effect (an increase in biomass of about 240% with respect to control) was observed when culturing Laetiporus sulphureus, the intrinsically high level of oxidative metabolism of which was significantly lowered by the presence of the studied additives. It was shown that the growth-enhancing action of nanoparticles of fullerene C60 and its derivatives could not be attributed to photochemical reactions, particularly fullerene photoexcitation. Fullerene and its derivatives manifest a growth regulatory effect on bio-objects from different kingdoms of the living world (plants and fungi), which is indicative of these compounds’ mechanism of action based on a direct impact on fundamental, universal for all living beings, biophysical processes, primarily chain free-radical oxidation. Full article
(This article belongs to the Special Issue Isolation, Extraction and Purification of Fungal Natural Products)
Show Figures

Figure 1

Back to TopTop