Stimuli-Responsive Polymers: Current Advances and Future Perspectives

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biomacromolecules, Biobased and Biodegradable Polymers".

Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 541

Special Issue Editor

School of Biomedical Sciences, University of Otago, Hercus Rm 339, 270 Great King St, 9016 Dunedin, New Zealand
Interests: nitric oxide; nitric oxide synthase inhibitors; nitric oxide releasing biomaterials; anti-cancer nanoparticles; polymeric prodrugs

Special Issue Information

Dear Colleagues,

With the advent of smart stimuli-responsive polymers, nowadays, it is possible to develop materials which simulate biological intelligence observed in nature. In particular, stimuli-responsive drug delivery (SRDDS) systems that allow the delivery of conventional drugs in spatial-, temporal- and dosage-controlled fashions have become a research hotspot in recent years. The stimuli can be from an external source such as light, near IR, ultrasound, X-ray and magnetic field or internal triggers such as heat, pH, oxidative stress and enzymatic reactions. Nevertheless, despite the sophisticated technology and promising preclinical results, the clinical translation of most of these technologies faces several major challenges such as chronic toxicities, long-term stability, biodistribution and selectivity and targeting efficacy in vivo.

Hence, the current research topic aims to cover the recent developments of SRDDS and barriers which hurdles their clinical application. In general, the scope of the current research topic involves the pathophysiology of some of the disease and biological conditions that can be used as stimuli for targeting, smart and responsive biomaterials, current developments of SRDDS, and limitations of the currently available systems.

Dr. Houman Alimoradi
Guest Editor

Manuscript Submission Information

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Keywords

  • stimuli-responsive drug delivery
  • redox-responsive drug delivery
  • hypoxia-responsive drug delivery
  • pH-responsive drug delivery
  • enzyme-responsive drug delivery
  • near ir-responsive drug delivery
  • light responsive drug delivery
  • thermo-responsive drug delivery
  • magnetic responsive drug delivery
  • ultrasound responsive drug delivery
  • X-ray responsive drug delivery

Published Papers

There is no accepted submissions to this special issue at this moment.
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