Special Issue "Advances in Bio-Based Polymeric Materials II"

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biomacromolecules, Biobased and Biodegradable Polymers".

Deadline for manuscript submissions: 31 October 2023 | Viewed by 1525

Special Issue Editor

Department of Biomedical Engineering, Khalifa University of Science and Technology, Abu Dhabi 127788, United Arab Emirates
Interests: bio-polymers; cellular biophysics; cell mechanics; cell imaging; actin
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

“Bio-Based Polymeric Materials” encompass a broad spectrum of biofunctional macromolecules ranging from naturally occurring polymers to biodegradable polymers and polymeric biocomposites to bioinspired synthetic polymers. Recent advances in the synthesis, purification, fabrication, functionalization, and characterization of biobased polymeric materials have opened new avenues for emerging applications in nucleic acid delivery, tissue engineering, controlled release, biological imaging, antimicrobial therapeutics, soft robotics, bioseparations, etc. In order to propel the development of these novel materials for practical devices, further elucidations of structure–property–biofunction relationships under physiological or bioprocess conditions with innovative approaches will be critical.

This Special Issue of the journal Polymers welcomes the submission of original research papers and reviews from all multidisciplinary areas of “Bio-Based Polymeric Materials”, including, but not limited to: 

  • Live-cell imaging probes;
  • Nucleic acid carriers;
  • Polymeric scaffold;
  • Controlled release devices;
  • Regenerative medicine;
  • Polymeric hydrogels;
  • Soft nanorobotics;
  • Surface functionalization;
  • Layer-by-layer biomaterials;
  • Polymer–biomembrane interactions;
  • Biodegradable polymers;
  • Molecular biosensors;
  • Biophysical characterizations;
  • Antimicrobial coating;
  • Vaccine formulation.

Prof. Dr. Vincent Chan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • live-cell imaging probes
  • nucleic acid carriers
  • polymeric scaffold
  • controlled release devices
  • regenerative medicine
  • polymeric hydrogels
  • soft nanorobotics
  • surface functionalization
  • layer-by-layer biomaterials
  • polymer–biomembrane interactions
  • biodegradable polymers
  • molecular biosensors
  • biophysical characterizations
  • antimicrobial coating
  • vaccine formulation

Published Papers (1 paper)

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One-Pot Synthesis of Double-Network PEG/Collagen Hydrogel for Enhanced Adipogenic Differentiation and Retrieval of Adipose-Derived Stem Cells
Polymers 2023, 15(7), 1777; https://doi.org/10.3390/polym15071777 - 03 Apr 2023
Cited by 1 | Viewed by 1226
Hydrogels are widely used in stem cell therapy due to their extensive tunability and resemblance to the extracellular matrix (ECM), which has a three-dimensional (3D) structure. These features enable various applications that enhance stem cell maintenance and function. However, fast and simple hydrogel [...] Read more.
Hydrogels are widely used in stem cell therapy due to their extensive tunability and resemblance to the extracellular matrix (ECM), which has a three-dimensional (3D) structure. These features enable various applications that enhance stem cell maintenance and function. However, fast and simple hydrogel fabrication methods are desirable for stem cells for efficient encapsulation and to reduce adverse effects on the cells. In this study, we present a one-pot double-crosslinked hydrogel consisting of polyethylene glycol (PEG) and collagen, which can be prepared without the multi-step sequential synthesis of each network, by using bio-orthogonal chemistry. To enhance the adipogenic differentiation efficiency of adipose-derived stem cells (ADSCs), we added degradable components within the hydrogel to regulate matrix stiffness through cell-mediated degradation. Bio-orthogonal reactions used for hydrogel gelation allow rapid gel formation for efficient cell encapsulation without toxic by-products. Furthermore, the hybrid network of synthetic (PEG) and natural (collagen) components demonstrated adequate mechanical strength and higher cell adhesiveness. Therefore, ADSCs grown within this hybrid hydrogel proliferated and functioned better than those grown in the single-crosslinked hydrogel. The degradable elements further improved adipogenesis in ADSCs with dynamic changes in modulus during culture and enabled the retrieval of differentiated cells for potential future applications. Full article
(This article belongs to the Special Issue Advances in Bio-Based Polymeric Materials II)
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