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Special Issue "Natural Polymers: Isolation, Modification, and Applications"

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A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biomacromolecules, Biobased and Biodegradable Polymers".

Deadline for manuscript submissions: 25 January 2024 | Viewed by 3434

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Dr. Lei Wang

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Guest Editor

College of Food Science and Engineering, Ocean University of China, Qingdao 266003, China
Interests: marine natural products; human health; skin aging
Special Issues, Collections and Topics in MDPI journals

Dr. Caoxing Huang

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Guest Editor

College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China
Interests: bioapplication of biomass-derived materials; toxicity assessment of environmental pollutants; biorefinery; cellulose
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Natural polymers such as carbohydrates, proteins, and nucleic acids possess various health benefits, including antioxidant, anti-obesity, anti-inflammatory, anti-diabetes, and anticancer bioactivities. Based on their health benefits, bioactive natural polymers have been utilized in pharmaceutical, nutraceutical, and cosmeceutical industries.

To obtain natural polymers from marine and terrestrial organisms, physical, chemical, biological, and combined methods have been widely investigated. Despite the tremendous progress that has been made in the development of these isolation and purification technologies, there are still some problems, such as the high amount of consumption of chemical solvents, which can easily be destroyed and deactivated. Thus, finding environmentally friendly, sustainable, and industrialized technologies to obtain natural polymers from marine and terrestrial organisms is still remarkably challenging.

This Special Issue presents studies on advances in isolation, modification, and applications of natural polymers from marine and terrestrial organisms, including isolation, characterization, modification, and bioactivity evaluation.

Dr. Lei Wang
Dr. Caoxing Huang
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

polysaccharides
human health
nutraceutical
cosmeceutical
pharmaceutical

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Research

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Open AccessArticle

Protective Effect of Sargassum fusiforme Fucoidan against Ethanol-Induced Oxidative Damage in In Vitro and In Vivo Models

and

Polymers 2023, 15(8), 1912; https://doi.org/10.3390/polym15081912 - 17 Apr 2023

Cited by 1 | Viewed by 1010

Abstract

Our previous studies have evaluated the bioactivities of a fucoidan isolated from Sargassum fusiforme (SF-F). To further investigate the health benefit of SF-F, in the present study, the protective effect of SF-F against ethanol (EtOH)-induced oxidative damage has been evaluated in in vitro and in vivo models. SF-F effectively improved the viability of EtOH-treated Chang liver cells by suppressing apoptosis. In addition, the in vivo test results indicate that SF-F significantly and dose-dependently increased the survival rate of zebrafish treated with EtOH. Further research results show that this action works through decreasing cell death via reduced lipid peroxidation by scavenging intracellular reactive oxygen species in EtOH-stimulated zebrafish. These results indicate that SF-F effectively protected Chang liver cells and zebrafish against EtOH-induced oxidative damage and suggest the potential of SF-F to be used as an ingredient in the functional food industry. Full article

(This article belongs to the Special Issue Natural Polymers: Isolation, Modification, and Applications)

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Chitosan Nanoparticles for Gastroesophageal Reflux Disease Treatment

Yedi Herdiana

Polymers 2023, 15(16), 3485; https://doi.org/10.3390/polym15163485 - 20 Aug 2023

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Abstract

Gastroesophageal Reflux Disease (GERD) is a chronic ailment that results from the backward flow of stomach acid into the esophagus, causing heartburn and acid regurgitation. This review explores nanotechnology as a novel treatment approach for GERD. Chitosan nanoparticles (CSNPs) offer several advantages, including biocompatibility, biodegradability, and targeted drug delivery capabilities. CSNPs have been extensively studied due to their ability to encapsulate and release medications in a controlled manner. Different nanoparticle (NP) delivery systems, including gels, microspheres, and coatings, have been developed to enhance drug retention, drug targeting, and controlled release in the esophagus. These nanoparticles can target specific molecular pathways associated with acid regulation, esophageal tissue protection, and inflammation modulation. However, the optimization of nanoparticle formulations faces challenges, including ensuring stability, scalability, and regulatory compliance. The future may see CSNPs combined with other treatments like proton pump inhibitors (PPIs) or mucosal protectants for a synergistic therapeutic approach. Thus, CSNPs provide exciting opportunities for novel GERD treatment strategies. Full article

(This article belongs to the Special Issue Natural Polymers: Isolation, Modification, and Applications)

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Chitosan-Based Polymer Blends for Drug Delivery Systems

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Polymers 2023, 15(9), 2028; https://doi.org/10.3390/polym15092028 - 25 Apr 2023

Cited by 1 | Viewed by 1405

Abstract

Polymers have been widely used for the development of drug delivery systems accommodating the regulated release of therapeutic agents in consistent doses over a long period, cyclic dosing, and the adjustable release of both hydrophobic and hydrophilic drugs. Nowadays, polymer blends are increasingly employed in drug development as they generate more promising results when compared to those of homopolymers. This review article describes the recent research efforts focusing on the utilization of chitosan blends with other polymers in an attempt to enhance the properties of chitosan. Furthermore, the various applications of chitosan blends in drug delivery are thoroughly discussed herein. The literature from the past ten years was collected using various search engines such as ScienceDirect, J-Gate, Google Scholar, PubMed, and research data were compiled according to the various novel carrier systems. Nanocarriers made from chitosan and chitosan derivatives have a positive surface charge, which allows for control of the rate, duration, and location of drug release in the body, and can increase the safety and efficacy of the delivery system. Recently developed nanocarriers using chitosan blends have been shown to be cost-effective, more efficacious, and prolonged release carriers that can be incorporated into suitable dosage forms. Full article

(This article belongs to the Special Issue Natural Polymers: Isolation, Modification, and Applications)

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Special Issue "Natural Polymers: Isolation, Modification, and Applications"

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