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Polymers
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Functional Gelatin II
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Functional Gelatin II

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biomacromolecules, Biobased and Biodegradable Polymers".

Deadline for manuscript submissions: closed (15 September 2023) | Viewed by 14980

Special Issue Editor

Prof. Dr. Svetlana Deckach

E-Mail Website
Guest Editor
Chemistry Department, Murmansk State Technical University, Murmansk, Russia
Interests: macromolecules; biopolymers; proteins; drug-delivery systems; colloid and surface chemistry; rheology; pharmaceutical chemistry
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Gelatin—the product of the breakdown of the fibrillar protein collagen—is one of the most widely used natural biopolymers in the industry. The surface activity and the unique ability of the thermo-reversible structure formation determine the demand for gelatin in various fields, including the food industry, medicine, pharmaceuticals, biotechnology, and so on. Gelatin exhibits its properties most clearly in multicomponent systems. A deliberate change in the properties of gelatin, resulting from its complexation with surfactants, polysaccharides, polyelectrolytes, and so on, is the key for industrial use, and, above all, for food technologies. The relationship between molecular weight distribution, secondary structure and functional properties, structural stability and rheological behavior, interactions between complexing components, distribution between the bulk phases and various kinds of interfaces, are basic aspects of this field. This Special Issue welcomes all contributions from a comprehensive range of expertise in the field. Subjects like phase separation, surface phenomena, drug delivery, foams, emulsions, gels, and 3D printing are welcome. Proposals are also welcome from the many industries that manufacture gelatins or gelatin products, including food, pharmaceutical, cosmetic, and medicine industries, to name a few.

Prof. Dr. Svetlana Derkatch
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gelatin
  • biopolymers
  • bioactive
  • biomaterials

Published Papers (4 papers)

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Research

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13 pages, 1922 KiB  
Article
Evaluation and Characterization of Hard-Shell Capsules Formulated by Using Goatskin Gelatin
by Zilhadia Zilhadia, Yahdiana Harahap, Irwandi Jaswir and Effionora Anwar
Polymers 2022, 14(20), 4416; https://doi.org/10.3390/polym14204416 - 19 Oct 2022
Cited by 5 | Viewed by 6388
Abstract
Gelatin is used as an additive in medicine, food, and cosmetics. Gelatin from goatskin is a new excipient that has not been explored by researchers, including for hard-shell capsules. The aim of this study was to evaluate and characterize the hard-shell capsules produced [...] Read more.
Gelatin is used as an additive in medicine, food, and cosmetics. Gelatin from goatskin is a new excipient that has not been explored by researchers, including for hard-shell capsules. The aim of this study was to evaluate and characterize the hard-shell capsules produced from goatskin gelatin. The goatskin gelatin was extracted by an acid hydrolysis method, and the functional properties were investigated. Hard-shell capsules were then produced from goatskin gelatin, evaluated, and characterized. The gelatin extracted from goatskin had 56.9% ± 0.95 clarity and a pH of 5.11 ± 0.09, 97.51% ± 1.1 protein content, 9.23% ± 0.08 water content, 0.18% ± 0.07 ash content, 2.08% ± 0.35 fat content, gel strength of 298 ± 2.64 gbloom, and viscosity of 27.33 ± 2.07 mPs. The gelatin has met the requirements to be made into hard-shell capsules. The average weight of the hard-shell capsules produced was 96.9 mg with 8.69 standard deviation. The average size of the body and cap length was 18.84 ± 0.64 mm and 10.98 ± 0.30 mm, respectively. The results of capsule evaluation and characterization were as follows: the pH was 4.82 ± 1,27, water content was 10.03 ± 0.21, disintegration time was 4.02 ± 2.09 min, and there was no microbial growth. Thus, the capsules made have met the requirements and can be produced in a large quantity. Full article
(This article belongs to the Special Issue Functional Gelatin II)
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14 pages, 5896 KiB  
Article
Fabrication and Characterization of Gelatin/Polyvinyl Alcohol Composite Scaffold
by Mengwen Sun, Yajuan Wang, Lihui Yao, Ya Li, Yunxuan Weng and Dan Qiu
Polymers 2022, 14(7), 1400; https://doi.org/10.3390/polym14071400 - 30 Mar 2022
Cited by 18 | Viewed by 3184
Abstract
In this study, porous scaffold materials based on polyvinyl alcohol (PVA) and gelatin (Gel) were successfully fabricated and characterized. The mechanism of the reaction, morphology, and crystallinity were investigated by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), X-ray diffraction (XRD), and [...] Read more.
In this study, porous scaffold materials based on polyvinyl alcohol (PVA) and gelatin (Gel) were successfully fabricated and characterized. The mechanism of the reaction, morphology, and crystallinity were investigated by Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). In addition, thermogravimetric analysis (TGA) was performed together with differential scanning calorimetry (DSC) for examining the thermostability and phase transformation of the scaffolds. Degradation and swelling studies of PVA/Gel composite scaffold materials were performed in phosphate-buffered saline. Finally, the mechanical performances had been determined. According to the results, the polymer matrix that was formed by the combination of PVA and gelatin had better thermal stability. The synthesized composite scaffold was amorphous in nature. The addition of gelatin did not affect the fishbone-like microstructure of PVA, which ensures the excellent mechanical properties of the PVA scaffold. The denaturation temperature and elastic modulus of the PVA scaffold were improved by the gelatin addition, but the physical and chemical properties of the PVA scaffold were weakened when the gelatin content exceeded 10%. In addition, the PVA-10G sample has suitable degradability. Therefore, the PVA/Gel composite scaffold might potentially be applied in the field of tissue engineering that demands high strength. Full article
(This article belongs to the Special Issue Functional Gelatin II)
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18 pages, 6725 KiB  
Article
Development and Characterization of Biocompatible Membranes from Natural Chitosan and Gelatin for Pervaporative Separation of Water–Isopropanol Mixture
by Akshay S. Kulkarni, Ashok M. Sajjan, T. M. Yunus Khan, Irfan Anjum Badruddin, Sarfaraz Kamangar, Nagaraj R. Banapurmath, Narasimha H. Ayachit, M. Ashwini and A. Sharanappa
Polymers 2021, 13(17), 2868; https://doi.org/10.3390/polym13172868 - 26 Aug 2021
Cited by 9 | Viewed by 2076
Abstract
Natural polymers have attracted a lot of interest in researchers of late as they are environmentally friendly, biocompatible, and possess excellent characters. Membranes forming natural polymers have provided a whole new dimension to the separation technology. In this work, chitosan-gelatin blend membranes were [...] Read more.
Natural polymers have attracted a lot of interest in researchers of late as they are environmentally friendly, biocompatible, and possess excellent characters. Membranes forming natural polymers have provided a whole new dimension to the separation technology. In this work, chitosan-gelatin blend membranes were fabricated using chitosan as the base and varying the amount of gelatin. Transport, mechanical, and surface characteristics of the fabricated membranes were examined in detail by means of the characterizing techniques such as Fourier transform infrared spectroscopy, differential scanning colorimetry, wide angle X-ray diffraction, scanning electron microscope, and thermogravimetric analysis. In order to analyze the water affinity of the developed blend chitosan-gelatin membranes, the percentage degree of swelling was examined. Out of the fabricated membranes, the membrane loaded with 15 mass% of gelatin exhibited the better pervaporation performance with a pervaporation separation index value of 266 at 30 °C for the solution containing 10% in terms of the mass of water, which is the highest among the contemporary membranes. All the fabricated membranes were stable during the pervaporation experiments, and permeation flux of water for the fabricated membranes was dominant in the overall total permeation flux, signifying that the developed membranes could be chosen for efficient separation of water–isopropanol mixture on a larger scale. Full article
(This article belongs to the Special Issue Functional Gelatin II)
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Review

Jump to: Research

18 pages, 8882 KiB  
Review
Intermolecular Interactions in the Formation of Polysaccharide-Gelatin Complexes: A Spectroscopic Study
by Svetlana R. Derkach, Nikolay G. Voron’ko and Yulia A. Kuchina
Polymers 2022, 14(14), 2777; https://doi.org/10.3390/polym14142777 - 07 Jul 2022
Cited by 11 | Viewed by 2459
Abstract
Gelatin, due to its gelling and stabilizing properties, is one of the widely used biopolymers in biotechnology, medicine, pharmaceuticals, and the food industry. One way to modify the characteristics of gelatin is molecular modification by forming non-covalent polyelectrolyte complexes with polysaccharides based on [...] Read more.
Gelatin, due to its gelling and stabilizing properties, is one of the widely used biopolymers in biotechnology, medicine, pharmaceuticals, and the food industry. One way to modify the characteristics of gelatin is molecular modification by forming non-covalent polyelectrolyte complexes with polysaccharides based on the self-organization of supramolecular structures. This review summarizes recent advances in the study of various types and the role of intermolecular interactions in the formation of polysaccharide-gelatin complexes, and conformational changes in gelatin, with the main focus on data obtained by spectroscopic methods: UV, FT-IR, and 1H NMR spectroscopy. In the discussion, the main focus is on the complexing polysaccharides of marine origin-sodium alginate, κ-carrageenan, and chitosan. The prospects for creating polysaccharide-gelatin complexes with desired physicochemical properties are outlined. Full article
(This article belongs to the Special Issue Functional Gelatin II)
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