Special Issue "Advanced Biodegradable Polymer Scaffolds for Tissue Engineering II"

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biomacromolecules, Biobased and Biodegradable Polymers".

Deadline for manuscript submissions: 20 October 2023 | Viewed by 826

Special Issue Editors

Department of Science and Engineering of Oxide Materials and Nanomaterials, University Politehnica of Bucharest, 011061 Bucharest, Romania
Interests: nanomaterials; drug delivery systems; biomimetic materials; biogenic calcium sources; composite scaffolds
Special Issues, Collections and Topics in MDPI journals
Department of Science and Engineereing of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science, Politehnica University of Bucharest, RO-011061 Bucharest, Romania
Interests: synthesis and characterization of nanobiomaterials; polymers; pharmaceutical nanotechnology; drug delivery; anti-biofilm surfaces; nanomodified surfaces; natural products
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

With its multidisciplinary approach, this Special Issue aims to gather the most recent and important knowledge in top-priority scientific fields, such as health and emerging technologies. Tissue and organ regeneration are still a challenge in contemporary medical practices. There are currently numerous treatment options, which include the possibility of transplantation, mechanical devices, artificial prostheses, surgery, and drug therapy—yet when discussing massive tissue damage, a major issue is represented by the development of biodegradable scaffolds, with proper mechanical and biological properties, to create a balance between tissue resorption and formation. Apart from the biocompatibility of the implanted materials, another limitation arises from the high risk of infection associated with surgical intervention. This Special Issue will focus on modern synthesis routes and characterization techniques to design tissue regeneration materials with enhanced properties in terms of antimicrobial effect and biocompatibility requirements (e.g., 3D porous composite scaffolds with controlled release of bioactive compounds, scaffolds based on biotemplates, or naturally derived biomaterials, with the potential to mimic the native tissue).

Dr. Ionela Andreea Neacsu
Dr. Alexandru Grumezescu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • polymers
  • scaffolds
  • composites
  • porous materials
  • wound dressings
  • 3D printing
  • biomedical applications
  • cell proliferation
  • biodegradability
  • tissue engineering

Published Papers (1 paper)

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Research

Article
Development of Silk Fibroin-Based Non-Crosslinking Thermosensitive Bioinks for 3D Bioprinting
Polymers 2023, 15(17), 3567; https://doi.org/10.3390/polym15173567 - 28 Aug 2023
Viewed by 443
Abstract
Three-dimensional (3D) bioprinting holds great promise for tissue engineering, allowing cells to thrive in a 3D environment. However, the applicability of natural polymers such as silk fibroin (SF) in 3D bioprinting faces hurdles due to limited mechanical strength and printability. SF, derived from [...] Read more.
Three-dimensional (3D) bioprinting holds great promise for tissue engineering, allowing cells to thrive in a 3D environment. However, the applicability of natural polymers such as silk fibroin (SF) in 3D bioprinting faces hurdles due to limited mechanical strength and printability. SF, derived from the silkworm Bombyx mori, is emerging as a potential bioink due to its inherent physical gelling properties. However, research on inducing thermosensitive behavior in SF-based bioinks and tailoring their mechanical properties to specific tissue requirements is notably lacking. This study addresses these gaps through the development of silk fibroin-based thermosensitive bioinks (SF-TPBs). Precise modulation of gelation time and mechanical robustness is achieved by manipulating glycerol content without recourse to cross-linkers. Chemical analysis confirms β-sheet conformation in SF-TPBs independent of glycerol concentration. Increased glycerol content improves gelation kinetics and results in rheological properties suitable for 3D printing. Overall, SF-TPBs offer promising prospects for realizing the potential of 3D bioprinting using natural polymers. Full article
(This article belongs to the Special Issue Advanced Biodegradable Polymer Scaffolds for Tissue Engineering II)
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