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Special Issue "Research Progress on Chitosan Applications"

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A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biomacromolecules, Biobased and Biodegradable Polymers".

Deadline for manuscript submissions: 20 October 2023 | Viewed by 1612

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Special Issue Editors

Dr. William Facchinatto
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Guest Editor

Aveiro Institute of Materials, University of Aveiro, CICECO/UA, St. Santiago, 3810-193 Aveiro, Portugal
Interests: biobased polymers; biomaterials; nanomaterials; NMR methods; micro/nanomotors

Prof. Dr. Sérgio Paulo Campana-Filho

E-Mail Website
Guest Editor

São Carlos Institute of Chemistry, University of São Paulo, IQSC/USP, Ave. Trabalhador são-carlense, 400, São Carlos 13560-970, SP, Brazil
Interests: chitin; chitosan; chemical derivatization; structural and physcochemical characterization; chitosan-based materials
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Special Issue Information

Dear Colleagues,

You are invited to submit a research paper to this Special Issue entitled “Research Progress in Chitosan Applications”. During the past few decades, novel functional materials based on chitosan have been exploited for the most essential and challenging research fields. Owing to the notable versatility of chitosan, meaningful outcomes and applications have emerged, leading the progress and development of new perspectives in the controlled delivery of pharmaceuticals, plant biocontrol agents and tissue engineering as active platforms for electronic and wound healing devices, food packaging, flame retardant and the removal of toxic organic effluents and heavy metals. As a result, unprecedented opportunities are continuously arising and opening the path for advanced chitosan-based developments. We dedicate this Special Issue to highlighting the most recent achievements regarding chitosan applications and impactful knowledge for further innovative studies.

Dr. William Facchinatto
Prof. Dr. Sérgio Paulo Campana-Filho
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

chitosan
biopolymers
chitin
nanotechnology
biomaterial
chemically modified derivatives
biomedical applications
environmental remediation
spectroscopy characterization
biosensing
micro/nanomotors

Published Papers (3 papers)

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Research

Open AccessArticle

Chitosan Coatings Modified with Nanostructured ZnO for the Preservation of Strawberries

Dulce J. García-García

G. F. Pérez-Sánchez

H. Hernández-Cocoletzi

M. G. Sánchez-Arzubide

M. L. Luna-Guevara

E. Rubio-Rosas

Rambabu Krishnamoorthy

and

C. Morán-Raya

Polymers 2023, 15(18), 3772; https://doi.org/10.3390/polym15183772 - 15 Sep 2023

Viewed by 287

Abstract

Strawberries are highly consumed around the world; however, the post-harvest shelf life is a market challenge to mitigate. It is necessary to guarantee the taste, color, and nutritional value of the fruit for a prolonged period of time. In this work, a nanocoating based on chitosan and ZnO nanoparticles for the preservation of strawberries was developed and examined. The chitosan was obtained from residual shrimp skeletons using the chemical method, and the ZnO nanoparticles were synthesized by the close-spaced sublimation method. X-ray diffraction, scanning electron microscopy, electron dispersion analysis, transmission electron microscopy, and infrared spectroscopy were used to characterize the hybrid coating. The spaghetti-like ZnO nanoparticles presented the typical wurtzite structure, which was uniformly distributed into the chitosan matrix, as observed by the elemental mapping. Measurements of color, texture, pH, titratable acidity, humidity content, and microbiological tests were performed for the strawberries coated with the Chitosan/ZnO hybrid coating, which was uniformly impregnated on the strawberries’ surface. After eight days of storage, the fruit maintained a fresh appearance. The microbial load was reduced because of the synergistic effect between chitosan and ZnO nanoparticles. Global results confirm that coated strawberries are suitable for human consumption. Full article

(This article belongs to the Special Issue Research Progress on Chitosan Applications)

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Open AccessArticle

Chitosan Resin-Modified Glass Ionomer Cement Containing Epidermal Growth Factor Promotes Pulp Cell Proliferation with a Minimum Effect on Fluoride and Aluminum Release

Chanothai Hengtrakool

Supreya Wanichpakorn

and

Ureporn Kedjarune-Leggat

Polymers 2023, 15(17), 3511; https://doi.org/10.3390/polym15173511 - 23 Aug 2023

Viewed by 408

Abstract

The development of biomaterials that are able to control the release of bioactive molecules is a challenging task for regenerative dentistry. This study aimed to enhance resin-modified glass ionomer cement (RMGIC) for the release of epidermal growth factor (EGF). This RMGIC was formulated from RMGIC powder supplemented with 15% (w/w) chitosan at a molecular weight of either 62 or 545 kDa with 5% bovine serum albumin mixed with the same liquid component as the Vitrebond. EGF was added while mixing. ELISA was used to determine EGF release from the specimen immersed in phosphate-buffered saline at 1 h, 3 h, 24 h, 3 d, 1 wk, 2 wks, and 3 wks. Fluoride and aluminum release at 1, 3, 5, and 7 d was measured by electrode and inductively coupled plasma optical emission spectrometry. Pulp cell viability was examined through MTT assays and the counting of cell numbers using a Coulter counter. The RMGIC with 65 kDa chitosan is able to prolong the release of EGF for significantly longer than RMGIC for at least 3 wks due to its retained bioactivity in promoting pulp cell proliferation. This modified RMGIC can prolong the release of fluoride, with a small amount of aluminum also released for a limited time. This biomaterial could be useful in regenerating pulp–dentin complexes. Full article

(This article belongs to the Special Issue Research Progress on Chitosan Applications)

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Open AccessArticle

Injectable Lyophilized Chitosan-Thrombin-Platelet-Rich Plasma (CS-FIIa-PRP) Implant to Promote Tissue Regeneration: In Vitro and Ex Vivo Solidification Properties

and

Polymers 2023, 15(13), 2919; https://doi.org/10.3390/polym15132919 - 30 Jun 2023

Viewed by 494

Abstract

Freeze-dried chitosan formulations solubilized in platelet-rich plasma (PRP) are currently evaluated as injectable implants with the potential for augmenting the standard of care for tissue repair in different orthopedic conditions. The present study aimed to shorten the solidification time of such implants, leading to an easier application and a facilitated solidification in a wet environment, which were direct demands from orthopedic surgeons. The addition of thrombin to the formulation before lyophilization was explored. The challenge was to find a formulation that coagulated fast enough to be applied in a wet environment but not too fast, which would make handling/injection difficult. Four thrombin concentrations were analyzed (0.0, 0.25, 0.5, and 1.0 NIH/mL) in vitro (using thromboelastography, rheology, indentation, syringe injectability, and thrombin activity tests) as well as ex vivo (by assessing the implant’s adherence to tendon tissue in a wet environment). The biomaterial containing 0.5 NIH/mL of thrombin significantly increased the coagulation speed while being easy to handle up to 6 min after solubilization. Furthermore, the adherence of the biomaterial to tendon tissues was impacted by the biomaterial-tendon contact duration and increased faster when thrombin was present. These results suggest that our biomaterial has great potential for use in regenerative medicine applications. Full article

(This article belongs to the Special Issue Research Progress on Chitosan Applications)

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