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Polymers
Special Issues
Polymeric Composite Nanomaterials in Medicine
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Polymeric Composite Nanomaterials in Medicine

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Composites and Nanocomposites".

Deadline for manuscript submissions: closed (25 September 2023) | Viewed by 3500

Special Issue Editors

Dr. Dmitry Kopitsyn

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Guest Editor
Department of Physical and Colloid Chemistry, Faculty of Chemical and Environmental Engineering, National University of Oil and Gas (Gubkin University), 65 Leninsky Prospekt, 119991 Moscow, Russia
Interests: polymers analysis; products testing and analysis; modified polymer material; analytical chemistry; gel permeation chromatography; nanocomposites
Special Issues, Collections and Topics in MDPI journals
Dr. Kirill Cherednichenko

E-Mail Website
Guest Editor
Department of Physical and Colloid Chemistry, Faculty of Chemical and Environmental Engineering, National University of Oil and Gas (Gubkin University), 65 Leninsky Prospekt, 119991 Moscow, Russia
Interests: TEM; SEM; FIB; nanocomposites; XRD; nanoclays; polymer foams
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Polymeric and composite materials are an essential part of modern medical technologies. Advanced nanomaterials with improved properties have attracted considerable attention owing to the emergence of healthcare technologies with enhanced treatment efficiency and diagnostic accuracy. The design of functional nanomaterials with desired properties for treatment and diagnosis has become possible only through systematic interdisciplinary research in chemistry, materials science and biology and the employment of special approaches and investigations methods in medicine.

This Special Issue aims to collect papers detailing developments and research in the field of polymeric composite nanomaterials for medical applications and their implementation in practice. We welcome original research papers as well as reviews focused on the design, synthesis and property characterization of polymeric composite nanomaterials for medical applications.

Dr. Dmitry Kopitsyn
Dr. Kirill Cherednichenko
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • nanocomposites
  • nanomaterials
  • nanomedicine
  • nanostructured materials
  • bionanocomposites
  • nanobioengineering
  • functional nanomaterials
  • polymer testing and analysis
  • polymer properties
  • polymer design
  • modified polymer material

Published Papers (2 papers)

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Research

15 pages, 9662 KiB  
Article
Composite Bone Cements with Enhanced Drug Elution
by Kirill Cherednichenko, Adeliya Sayfutdinova, Denis Rimashevskiy, Birzhan Malik, Andrey Panchenko, Maria Kopitsyna, Stanislav Ragnaev, Vladimir Vinokurov, Denis Voronin and Dmitry Kopitsyn
Polymers 2023, 15(18), 3757; https://doi.org/10.3390/polym15183757 - 14 Sep 2023
Cited by 2 | Viewed by 908
Abstract
Antibiotic-loaded bone cement (ALBC) has become an indispensable material in orthopedic surgery in recent decades, owing to the possibility of drugs delivery to the surgical site. It is applied for both infection prophylaxis (e.g., in primary joint arthroplasty) and infection treatment (e.g., in [...] Read more.
Antibiotic-loaded bone cement (ALBC) has become an indispensable material in orthopedic surgery in recent decades, owing to the possibility of drugs delivery to the surgical site. It is applied for both infection prophylaxis (e.g., in primary joint arthroplasty) and infection treatment (e.g., in periprosthetic infection). However, the introduction of antibiotic to the polymer matrix diminishes the mechanical strength of the latter. Moreover, the majority of the loaded antibiotic remains embedded in polymer and does not participate in drug elution. Incorporation of the various additives to ALBC can help to overcome these issues. In this paper, four different natural micro/nanoscale materials (halloysite, nanocrystalline cellulose, micro- and nanofibrillated cellulose) were tested as additives to commercial Simplex P bone cement preloaded with vancomycin. The influence of all four materials on the polymerization process was comprehensively studied, including the investigation of the maximum temperature of polymerization, setting time, and monomer leaching. The introduction of the natural additives led to a considerable enhancement of drug elution and microhardness in the composite bone cements compared to ALBC. The best combination of the polymerization rate, monomer leaching, antibiotic release, and microhardness was observed for the sample containing nanofibrillated cellulose (NFC). Full article
(This article belongs to the Special Issue Polymeric Composite Nanomaterials in Medicine)
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12 pages, 3918 KiB  
Article
Preparation and Characterization of Nanocomposite Hydrogels Based on Self-Assembling Collagen and Cellulose Nanocrystals
by Ya Li, Xiaotong Dong, Lihui Yao, Yajuan Wang, Linghui Wang, Zhiqiang Jiang and Dan Qiu
Polymers 2023, 15(5), 1308; https://doi.org/10.3390/polym15051308 - 05 Mar 2023
Cited by 4 | Viewed by 2139
Abstract
Collagen (Col) hydrogels are an important biomaterial with many applications in the biomedical sector. However, deficiencies, including insufficient mechanical properties and a rapid rate of biodegradation, hamper their application. In this work, nanocomposite hydrogels were prepared by combining a cellulose nanocrystal (CNC) with [...] Read more.
Collagen (Col) hydrogels are an important biomaterial with many applications in the biomedical sector. However, deficiencies, including insufficient mechanical properties and a rapid rate of biodegradation, hamper their application. In this work, nanocomposite hydrogels were prepared by combining a cellulose nanocrystal (CNC) with Col without any chemical modification. The high-pressure, homogenized CNC matrix acts as nuclei in the collagen’s self-aggregation process. The obtained CNC/Col hydrogels were characterized in terms of their morphology, mechanical and thermal properties and structure by SEM, rotational rheometer, DSC and FTIR, respectively. Ultraviolet-visible spectroscopy was used to characterize the self-assembling phase behavior of the CNC/Col hydrogels. The results showed an accelerated assembling rate with the increasing loading of CNC. The triple-helix structure of the collagen was preserved with a dosage of CNC of up to 15 wt%. The CNC/Col hydrogels demonstrated an improvement in both the storage modulus and thermal stability which is attributed to the interaction between the CNC and collagen by the hydrogen bonds. Full article
(This article belongs to the Special Issue Polymeric Composite Nanomaterials in Medicine)
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