Special Issue "Sustainability Functional Biopolymers for Future Precision Medicine: Processing and Translational Issues"

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Biomacromolecules, Biobased and Biodegradable Polymers".

Deadline for manuscript submissions: 15 March 2024 | Viewed by 1502

Special Issue Editors

Centre for Tissue Engineering and Regenerative Medicine (CTERM), Faculty of Medicine, 12th Floor Clinical Block, UKM Medical Centre, Jalan Yaacob Latiff, Cheras 56000, Kuala Lumpur, Malaysia
Interests: biomaterials; drug delivery system; skin wound healing; tissue engineering and regenerative medicine; cell delivery system; multifunctional smart materials; acellular tissue substitute; nanomaterials technology
Special Issues, Collections and Topics in MDPI journals
Department of Industrial Engineering, BIOtech Research Center, University of Trento, Via Sommarive 9, 38123 Trento, Italy
Interests: scaffolds design; regenerative medicine; nature-derived matrices; polymers functionalization; cells; tissue engineering; stem cell culture; cell culture; biocompatibility evaluations; bioink design; drug release systems; 3D in vitro models
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Precision medicine is a future essential advanced shifting era in clinical practice to construct suitable treatments that are based on an individual or subsets of patients. Functional biopolymer development faces a challenge due to the limitations of a “one-size-fits-all” approach to medicine intentions. Recently, a new concept of bioconvergence approaches has been introduced in regenerative medicine involving expertise from various fields, primarily synergistic life sciences, technology, and computerized systems. For this strategy to succeed, sustainable functional biopolymers must play a major role in future precision/personalized medicine. Certain issues should be addressed, especially in terms of the selection of compatible natural polymers, extraction, characterization, cell interaction, efficiency in preclinical models, mass production, and translational issues, mainly in clinical trial stages. This Special Issue will serve as a platform to gather new biopolymers, technologies, and perspectives from experts globally regarding the sustainability of authentic functional biopolymers.

Prof. Dr. Mh Busra Fauzi
Prof. Dr. Antonella Motta
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Recent Approaches to the Modification of Collagen Biomatrix as a Corneal Biomatrix and Its Cellular Interaction
Polymers 2023, 15(7), 1766; https://doi.org/10.3390/polym15071766 - 01 Apr 2023
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Over the last several decades, numerous modifications and advancements have been made to design the optimal corneal biomatrix for corneal epithelial cell (CECs) or limbal epithelial stem cell (LESC) carriers. However, researchers have yet to discover the ideal optimization strategies for corneal biomatrix [...] Read more.
Over the last several decades, numerous modifications and advancements have been made to design the optimal corneal biomatrix for corneal epithelial cell (CECs) or limbal epithelial stem cell (LESC) carriers. However, researchers have yet to discover the ideal optimization strategies for corneal biomatrix design and its effects on cultured CECs or LESCs. This review discusses and summarizes recent optimization strategies for developing an ideal collagen biomatrix and its interactions with CECs and LESCs. Using PRISMA guidelines, articles published from June 2012 to June 2022 were systematically searched using Web of Science (WoS), Scopus, PubMed, Wiley, and EBSCOhost databases. The literature search identified 444 potential relevant published articles, with 29 relevant articles selected based on inclusion and exclusion criteria following screening and appraising processes. Physicochemical and biocompatibility (in vitro and in vivo) characterization methods are highlighted, which are inconsistent throughout various studies. Despite the variability in the methodology approach, it is postulated that the modification of the collagen biomatrix improves its mechanical and biocompatibility properties toward CECs and LESCs. All findings are discussed in this review, which provides a general view of recent trends in this field. Full article
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