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Special Issue "Recent Progress in Solid Dispersion Technology 2.0"
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Physical Pharmacy and Formulation".
Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 17180
Special Issue Editor
Interests: solid dispersion; supersaturation; molecular assemblies; poorly soluble drugs; thermal analysis; polymorphism; solubilization
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
For over half a century, amorphous solid dispersion (ASD) has been recognized as a powerful formulation technology for improve oral absorption of poorly soluble drugs. In spite of this long history, novel important findings on ASD continue to be reported every year. In contrast to other solubilization technologies using additives—including surfactants, cyclodextrins, and organic solvents, which increase equilibrium solubility—amorphization does not disturb membrane permeation process. Thus, the probability of success in improvement of oral absorption is considered generally high for ASDs. In 2019, a Special Issue entitled “Recent Progress in Solid Dispersion Technology” was published to cover the cutting-edge research in this field. We have decided to publish an updated version to keep up with the new knowledge and technologies that have since emerged in ASD research.
This Special Issue welcomes any topics regarding recent progress in ASD technology, including, but not limited to:
- Prediction of oral absorption of drugs from ASDs;
- Prediction of long-term storage stability of ASDs;
- Relationship between compound property and its suitability for ASD;
- How to maintain supersaturated state after dissolution of ASDs;
- Novel manufacturing technologies involving ASD;
- Novel functional carriers for ASD;
- Novel analysis technologies for ASDs.
Dr. Kohsaku Kawakami
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- solid dispersion
- poorly soluble drug
- hot-melt extrusion