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6.9
5.4
Journals
Pharmaceutics
Special Issues
Current Trends in Dosage Form Development
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Special Issue "Current Trends in Dosage Form Development"

A special issue of Pharmaceutics (ISSN 1999-4923).

Deadline for manuscript submissions: closed (31 December 2010) | Viewed by 13954

Special Issue Editor

Prof. Dr. Roderick B. Walker

E-Mail Website
Guest Editor
Faculty of Pharmacy, Rhodes University, Makhanda 6140, South Africa
Interests: formulation; QbD; DoE; pharmaceutical analysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

This issue focuses on current approaches and trends in the development, formulation, manufacture and assessment of dosage forms.

Keywords

  • formulation
  • drug delivery
  • novel approaches to solving formulation issues
  • scale-up
  • manufacture
  • dosage form development

Published Papers (1 paper)

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Research

1672 KiB  
Article
Effect of Moisture on Powder Flow Properties of Theophylline
by
Niklas Sandler
, , and
Pharmaceutics 2010, 2(3), 275-290; https://doi.org/10.3390/pharmaceutics2030275 - 02 Jul 2010
Cited by 54 | Viewed by 13073
Abstract
Powder flow is influenced by environmental factors, such as moisture and static electricity, as well as powder related factors, such as morphology, size, size distribution, density, and surface area. Pharmaceutical solids may be exposed to water during storage in an atmosphere containing water [...] Read more.
Powder flow is influenced by environmental factors, such as moisture and static electricity, as well as powder related factors, such as morphology, size, size distribution, density, and surface area. Pharmaceutical solids may be exposed to water during storage in an atmosphere containing water vapor, or in a dosage form consisting of materials (e.g., excipients) that contain water and are capable of transferring in to other ingredients. The effect of moisture on powder flowability depends on the amount of water and its distribution. The aim of this work was to examine the effect of humidity on the flow properties of theophylline using information derived from solid-state analysis of the systems investigated. Full article
(This article belongs to the Special Issue Current Trends in Dosage Form Development)
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