Bioavailability of Topically Applied Drugs, Volume Ⅱ
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 419
Special Issue Editors
Interests: pharmaceutical technology; drug delivery; in vitro and in vivo models; biopharmaceutics; formulation
Special Issues, Collections and Topics in MDPI journals
Interests: pharmaceutical technology; drug delivery; in vitro and in vivo models; biopharmaceutics; formulation; skin, eye, nail, buccal and vaginal mucosae
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
One of the main requisites for successful topical therapy is to achieve an optimal drug concentration at the target site in order to minimize systemic side effects and to reduce the required dose to be applied. The improvement of the bioavailability of topically applied drugs represents a great challenge for researchers, as the different structures to be addressed (i.e., skin, eye, nail, buccal and vaginal mucosa) present anatomo-physiological barriers and selective transport mechanisms.
Different drug delivery strategies have been pursued in order to provide selective tissue permeation and distribution, such as the use of new functional materials, the synthesis of new pro-drugs, and the development of nanotechnologies, also endowed with stimuli-triggered drug release properties. Moreover, the assessment of drug bioavailability with in vitro pharmacokinetic modeling is an important issue, even with the availability of suitable biological models and drug pharmacokinetic studies.
This is the second volume of the Special Issue “Bioavailability of Topically Applied Drugs”. The first volume published 7 high quality papers. For this Special Issue, we welcome original research or review articles dealing with formulation strategies to improve the bioavailability of topically applied drugs and in vitro/in vivo evaluation.
Prof. Dr. Patrizia Chetoni
Dr. Silvia Tampucci
Guest Editors
Manuscript Submission Information
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