The Roles of Mesenchymal Stromal or Stem Cells in Cancer Therapy
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Gene and Cell Therapy".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 408
Special Issue Editors
Interests: regenerative medicine; tissue engineering; tumor microenvironment; mesenchymal stromal/stem cells; tumorigenesis
Interests: mesenchymal stromal/stem cells; cellular therapy; cancer treatment; adipogenesis; obesity
Special Issue Information
Dear Colleagues,
The promising therapeutic value of mesenchymal stromal/stem cells (MSCs) and their secretome in many diseases, including cancer, has inspired many studies investigating their properties and behaviour. MSCs, which can be sourced from many tissues, are multipotent cells. They are recruited to tumour sites, in which they display pleiotropic behaviour, including modulation of immune responses and inflammation. MSCs also participate in tissue repair and regeneration. Thus, they are considered key in tissue regeneration and as potential delivery vehicles for anti-cancer therapy. Additionally, MSCs at tumour sites initiate immune responses, which demonstrate both pro- and anti-tumorigenic effects. As such, a deeper understanding of their role in tissue regeneration, tumorigenesis and cancer treatment is required.
This Special Issue will present recent advances in our knowledge on MSC and its secretome in tissue regeneration, tumorigenesis and cancer therapy. Original research articles and reviews are welcome.
Dr. Kevin Dzobo
Dr. Melvin Anyasi Ambele
Guest Editors
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Keywords
- mesenchymal stromal/stem cells
- secretome
- tumour microenvironment
- tissue regeneration
- cellular therapy
- cancer therapy
- cancer
- immune modulation
- inflammation