Nanotechnological Strategies for Biomedical and Pharmaceutical Applications

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: closed (30 May 2023) | Viewed by 2252

Special Issue Editors

Division of Biotechnology, Department of Applied Science, University of Technology, Baghdad 10066, Iraq
Interests: clinical immunology; cancer biology; medical applications of nanoparticles; biotechnology; autophagy; drug delivery (nanotechnology)
Department of Chemistry, College of Science University of Misan, Maysan 62001, Iraq
Interests: design and fabrication of nanoparticles for anti-cancer drug delivery; electrospun nanofibers for wound dressing; green synthesis and antimicrobial activity of metal oxide nanoparticles; transfection of NSCs with neurotrophins using superparamagnetic iron oxide nanoparticles (SPIONs)

Special Issue Information

Dear Colleagues,

We are pleased to invite you contribute to this Special Issue titled “Nanotechnological Strategies for Biomedical and Pharmaceutical Applications”.

In recent years, nanotechnology has played a key role and had a significant impact in various fields. Nanotechnologies’ application in the fields of medicine and pharmaceutics, specifically in drug delivery, diagnostic methods, imaging and therapeutics, has attracted extensive attention. This Special Issue aims to highlight the progress and breakthroughs in nanomedicine in biomedical and pharmaceutical applications. Original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Novel design, synthesis and methodologies of nanomaterials for pharmaceutical applications;
  • Current progress in nanotechnology research for drug delivery systems;
  • Drug carriers and targeting by nanotechnology;
  • Strategies and formulations for controlled drug release;
  • Nanotechnology and cancer treatment;
  • Nanomaterials and nanotechnology in tissue engineering and regenerative nanomedicine;
  • Future nanotechnology strategies in therapeutics, diagnostics, and clinical pharmaceutics.

We look forward to receiving your contributions.

Prof. Dr. Majid Sakhi Jabir
Prof. Dr. Salim Albukhaty
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biosynthesis
  • nanoparticles
  • drug delivery
  • biomedical nanotechnology
  • nanocarriers
  • controlled drug release
  • therapeutic nanosystems

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

18 pages, 7984 KiB  
Article
Bioluminescence Imaging and ICP-MS Associated with SPION as a Tool for Hematopoietic Stem and Progenitor Cells Homing and Engraftment Evaluation
by Murilo M. Garrigós, Fernando A. Oliveira, Mariana P. Nucci, Javier B. Mamani, Olívia F. M. Dias, Gabriel N. A. Rego, Mara S. Junqueira, Cícero J. S. Costa, Lucas R. R. Silva, Arielly H. Alves, Nicole M. E. Valle, Luciana Marti and Lionel F. Gamarra
Pharmaceutics 2023, 15(3), 828; https://doi.org/10.3390/pharmaceutics15030828 - 03 Mar 2023
Viewed by 1414
Abstract
Bone marrow transplantation is a treatment for a variety of hematological and non-hematological diseases. For the transplant success, it is mandatory to have a thriving engraftment of transplanted cells, which directly depends on their homing. The present study proposes an alternative method to [...] Read more.
Bone marrow transplantation is a treatment for a variety of hematological and non-hematological diseases. For the transplant success, it is mandatory to have a thriving engraftment of transplanted cells, which directly depends on their homing. The present study proposes an alternative method to evaluate the homing and engraftment of hematopoietic stem cells using bioluminescence imaging and inductively coupled plasma mass spectrometry (ICP-MS) associated with superparamagnetic iron oxide nanoparticles. We have identified an enriched population of hematopoietic stem cells in the bone marrow following the administration of Fluorouracil (5-FU). Lately, the cell labeling with nanoparticles displayed the greatest internalization status when treated with 30 µg Fe/mL. The quantification by ICP-MS evaluate the stem cells homing by identifying 3.95 ± 0.37 µg Fe/mL in the control and 6.61 ± 0.84 µg Fe/mL in the bone marrow of transplanted animals. In addition, 2.14 ± 0.66 mg Fe/g in the spleen of the control group and 2.17 ± 0.59 mg Fe/g in the spleen of the experimental group was also measured. Moreover, the bioluminescence imaging provided the follow up on the hematopoietic stem cells behavior by monitoring their distribution by the bioluminescence signal. Lastly, the blood count enabled the monitoring of animal hematopoietic reconstitution and ensured the transplantation effectiveness. Full article
Show Figures

Figure 1

Back to TopTop