Selected papers from 7th APS International PharmSci Conference

A special issue of Pharmaceutics (ISSN 1999-4923).

Deadline for manuscript submissions: closed (31 March 2017) | Viewed by 17623

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Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, UK
Interests: particulate systems and formulations for drug delivery; vaccine adjuvanticity and diagnostics
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Scientific Administrator, The Academy of Pharmaceutical Sciences, Leicester LE4 9HA, UK
Interests: pharmaceutics; pharmaceutical education; inhalation drug delivery; drug development; pharmaceutical industry; project management

Special Issue Information

Dear Colleague,

The 7th APS International PharmSci Conference (http://www.ukpharmsci.org/whyattend_2016.asp), will be held at the Technology and Innovation Centre, University of Strathclyde, Glasgow, UK, from 5–7 September 2016.

The Conference is the leading UK Pharmaceutical Science conference, and has firmly established itself as the premier pharmaceutical science event in the UK. This Special Issue is dedicated as a memorial proceeding of the conference, and to provide a platform for academic and industrial institutions scientists, so as to seek and exchange updated and new knowledge on pharmaceutical science.

Participants of the conference will enjoy a 50% discount on the APC (article processing charges). We cordially invite you to contribute original research papers, reviews or communications to this Special Edition of Pharmaceutics.

Prof. Dr. Yvonne Perrie
Dr. Carol O’Connor
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Biopharmaceutics
  • Drug Metabolism
  • Pharmaceutical and biochemical analysis
  • Drug Delivery
  • Formulation
  • Pharmacology and Clinical Research
  • Pharmaceutical Technology
  • Pharmaceutical Microbiology

Published Papers (2 papers)

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Article
An Evaluation of the Binding Strength of Okra Gum and the Drug Release Characteristics of Tablets Prepared from It
by Amjad Hussain, Farah Qureshi, Nasir Abbas, Muhammad Sohail Arshad and Ejaz Ali
Pharmaceutics 2017, 9(2), 20; https://doi.org/10.3390/pharmaceutics9020020 - 2 Jun 2017
Cited by 15 | Viewed by 9483
Abstract
The aim of this study is to evaluate the adhesion ability of okra gum, which is gaining popularity as a tablet binder. For this purpose, gum was extracted from okra pods, and the binding strength of different concentrations (1%, 3%, and 5%) was [...] Read more.
The aim of this study is to evaluate the adhesion ability of okra gum, which is gaining popularity as a tablet binder. For this purpose, gum was extracted from okra pods, and the binding strength of different concentrations (1%, 3%, and 5%) was determined quantitatively. Additionally, naproxen sodium tablets were prepared by using okra gum as a binder and were evaluated for their properties including hardness, friability, disintegration time, and dissolution rate. The binding strength values were compared with that of pre-gelatinized starch, a commonly used tablet binder. The results from universal testing machine indicate that the binding strengths of all dispersions of okra increase as the concentration increases from 1% to 5% and ranges from 2.5 to 4.5 N, which are almost twice a high as those of pre-gelatinized starch. The tablets prepared with okra gum have shown good mechanical strength with hardness values of 7–8.5 kg/cm2 and a friability <1%, comparable to tablets prepared with starch. The disintegration time was longer (7.50 min with okra gum and 5.05 min with starch paste), and the drug release from these tablets was slower than the formulations with starch. The higher binding ability of okra gum probably linked with its chemical composition as it mainly contains galactose, rhamnose, and galacturonic acid. This study concludes that okra gum is a better binder than pre-gelatinized starch, it might be explored in future for introduction as a cost-effective binder in the pharmaceutical industry. Full article
(This article belongs to the Special Issue Selected papers from 7th APS International PharmSci Conference)
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Article
Accessing Mefenamic Acid Form II through High-Pressure Recrystallisation
by Nasir Abbas, Iain D. H. Oswald and Colin R. Pulham
Pharmaceutics 2017, 9(2), 16; https://doi.org/10.3390/pharmaceutics9020016 - 16 May 2017
Cited by 20 | Viewed by 7207
Abstract
High-pressure crystallisation has been successfully used as an alternative technique to prepare Form II of a non-steroidal anti-inflammatory drug, mefenamic acid (MA). A single crystal of Form II, denoted as high-pressure Form II, was grown at 0.3 GPa from an ethanolic solution by [...] Read more.
High-pressure crystallisation has been successfully used as an alternative technique to prepare Form II of a non-steroidal anti-inflammatory drug, mefenamic acid (MA). A single crystal of Form II, denoted as high-pressure Form II, was grown at 0.3 GPa from an ethanolic solution by using a diamond anvil cell. A comparison of the crystal structures shows that the efficient packing of molecules in Form II was enabled by the structural flexibility of MA molecules. Compression studies performed on a single crystal of Form I resulted in a 14% decrease of unit cell volume up to 2.5 GPa. No phase transition was observed up to this pressure. A reconstructive phase transition is required to induce conformational changes in the structure, which was confirmed by the results of crystallisation at high pressure. Full article
(This article belongs to the Special Issue Selected papers from 7th APS International PharmSci Conference)
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