Nanoparticles for RNA and DNA Delivery towards Personalized Medicine

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Gene and Cell Therapy".

Deadline for manuscript submissions: closed (10 February 2024) | Viewed by 306

Special Issue Editors


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Guest Editor
Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy
Interests: RNA and DNA delivery; liposomes; lipid nanoparticles; polymeric nanoparticles; precision nanomedicine; personalized medicine; gene editing; immunotherapy; self-assembling nanoparticles

E-Mail Website
Guest Editor
Department of Pharmacy, University of Naples Federico II, Via Domenico Montesano 49, 80131 Naples, Italy
Interests: nanotechnology; lipid nanovectors; skin delivery; nucleic acid delivery
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Special Issue Information

Dear Colleagues,

The recent development of omics technologies and large-scale biologic databases has fostered the emergence of personalized medicine approaches for the treatment of cancer and other diseases. Personalized medicine leverages patient information to design individualized treatments with improved efficacy compared to current therapies. While the conventional delivery of therapeutics faces several challenges in terms of payload stability and biodistribution, nanotechnology has the potential to overcome such challenges and to fully harness the promise of personalized medicine. In this context, lipid- and polymer-based nanoparticles represent a promising platform due to their ease of formulation, high biocompatibility and bioavailability, and the ability to deliver a wide range of payloads (including RNA and DNA).

This Special Issue aims to collate experts in the fields of nanotechnology and biology to share their latest research progress towards the development of lipid- or polymer-based formulations for RNA and DNA delivery towards personalized medicine approaches. Both original research articles and reviews are welcome in this Special Issue and research areas may include nucleic-acid-loaded nanoparticles for cancer immunotherapy or gene editing, nanoparticles with improved cellular targeting, or ready-to-assemble versatile nanoparticle platforms for therapeutic delivery. Manuscripts focused on the large-scale manufacture or scale-up of RNA or DNA formulations are also welcome.

We look forward to receiving your contributions.

Dr. Valeria Nele
Dr. Virginia Campani
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • RNA and DNA delivery
  • liposomes
  • lipid nanoparticles
  • polymeric nanoparticles
  • precision nanomedicine
  • personalized medicine
  • gene editing
  • immunotherapy
  • self-assembling nanoparticles

Published Papers

There is no accepted submissions to this special issue at this moment.
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