Nano-Based Drug Formulations towards Enhanced Bioavailability
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 329
Special Issue Editors
Interests: controlled-drug delivery; drug functionalization; metal-organic frameworks; inorganic nanoparticles; senescence; nanotherapy
Special Issue Information
Dear Colleagues,
One of the major challenges in de-novo-drug development is the poor-water-solubility of organic molecules and the lack of targeting moieties that improve their accumulation in the affected areas. The success of organic drugs, such as chemotherapies, is hampered by fatal side effects provoked by the high dosage of treatment. The emergence of nanomedicine and targeting therapies, together with a deeper understanding of the disease biology, has led to tremendous improvements in drug bioavailability since the 1980s. The controlled and targeted delivery of drugs in specific sites thanks to the introduction of several functionalities on the surface of nanoparticles, as well as drug conjugation with targeting molecules, can help to surpass the problems of the stability of the drugs, facilitate their transport to the damaged region and reduce the effective drug doses.
This Special Issue "Nano-Based Drug Formulations towards Enhanced Bioavailability" will serve to determine the state of the art of nanotechnology and its applicability in new nanomedicine systems against diseases.
Dr. Juan Francisco Blandez
Dr. Beatriz Lozano-Torres
Guest Editors
Manuscript Submission Information
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Keywords
- drug-delivery system
- organic molecular drug functionalization
- nanomedicine
- side-effect reduction
- drug targeting release
- new system diseases treatments
