Lipid Nanoparticles as Strategy to Improve Therapeutics of Antineoplastics: Targeting, Co-delivery and Synergic Excipients/Compounds
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 20 April 2024 | Viewed by 212
Special Issue Editors
Interests: drug delivery; lipid nanoparticles; nanocarriers; local anesthetics; anti-inflammatory
Special Issues, Collections and Topics in MDPI journals
Interests: lipidic nanoparticles; lipid nanocapsules; drug delivery; antineoplastics
Special Issue Information
Dear Colleagues,
Lipidic nanoparticles (LNs) are drug delivery systems that contain a lipid as the principal structural excipient. According to their nature (solid, liquid or blend), lipids can be classified into nanoemulsions, solid lipid nanoparticles, or lipid nanocapsules, etc. Moreover, LNs have a high upload capacity for lipophilic drugs, due to their lipid core, ideal for the majority of antineoplastics (AAs). Commercial formulations of lipophilic AAs are prepared with a large number of excipients that can increase the toxicity of AAs. These excipients, in addition to being non-selective, can potentialize the systemic toxicity of AAs. This Special Issue will be a collection of full papers, short communications, and review papers focuses on recent progress in new drug delivery technologies in cancer target therapy, gene therapy, immunotherapy and theragnostics. We wish to demonstrate the pre-clinical or clinical therapeutic advances that can be achieved by encapsulating AAs and other biomolecules (e.g., antibodies, proteins, nucleic acids) in LNs. The possibility of co-delivery in the same system (using drugs that are already used together in the clinic), the possibility of targeting the LNs (in addition to the EPR effect of the LNs), as well as the possibility of using natural excipients or synergistic antitumor action are subjects that will be featured in this Special Issue.
Prof. Dr. Eneida de Paula
Dr. Gustavo Henrique Rodrigues da Silva
Dr. Ludmilla David De Moura
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- lipid nanoparticles
- nanoemultions
- solid lipid nanoparticles
- lipid nanocapsules
- drug delivery
- antineoplastics
- anticancer
- cancer therapy
- gene therapy
- immunotherapy
- theragnostics
