Bioinsopired Mucoadhesive Polymers for Oral Drug Delivery

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".

Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 512

Special Issue Editors


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Guest Editor
School of Pharmacy, University of Camerino, Via Gentile III da Varano, Camerino, MC, Italy
Interests: drug delivery systems; colloids; hydrogels; thermogelling systems; mucoadhesion; surfactants; rheology
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Guest Editor
Pharmaceutical Technology & Biopharmacy, Institute of Pharmaceutical Sciences, University of Graz, Graz, Austria
Interests: nanomaterials; nanomedicine; drug delivery

Special Issue Information

Dear Colleagues,

Oral administration is one of the most widely used administration routes for local and systematic drug delivery, but drugs administered in this manner often face harsh conditions in the gastrointestinal (GI) tract, leading to their degradation and limited bioavailability. Optimal drug delivery systems are thus needed to protect drugs from degradation and enhance their distribution and penetration through GI barriers. One of the current trends in the design and development of drug delivery systems is the utilization of biocompatible and biodegradable multifunctional polymers with mucoadhesive properties. Mucoadhesive formulations for oral drug delivery exhibit many advantages over conventional orally delivered drugs, such as improved bioavailability and adherence to oral mucosa and enhanced retention time and permeability. This Special Issue aims to cover the next generation of polymers, with an emphasis on bioinspired and biomimetic polymers and their derivatives, which exhibit mucoadhesive properties, with an additional focus on novel properties for the further improvement of drug retention and bioavailability and smart drug delivery. Nano-based hybrid formulations conjugated with mucoadhesive polymers will also be highlighted.

Original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Bioinspired mucoadhesive polymers;
  • Mucoadhesive hydrogels;
  • Hybrid mucoadhesive nanoparticles;
  • Nanomedicines;
  • Design of drug delivery systems for local targeting (ulcers, IBD, etc.);
  • Drug release profiles;
  • In vitro, ex vivo and in vivo testing.

We look forward to receiving your contributions.

Dr. Giulia Bonacucina
Dr. Atiđa Selmani
Guest Editors

Manuscript Submission Information

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Keywords

  • mucoadhesion
  • bioinspired polymers
  • hybrid mucoadhesive systems
  • oral administration
  • targeted drug delivery
  • controlled release

Published Papers

There is no accepted submissions to this special issue at this moment.
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