Lipid Nanoparticles as Smart Vehicles of Therapeutic Compounds
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 1456
Special Issue Editors
Interests: lipid nanoparticles; antimicrobials; drug delivery; biopolymers; nanomedicine; drug development
Special Issue Information
Dear Colleagues,
The global context of increasing drug-resistant diseases requires urgent actions to avert serious sanitary and economic crises. If no alternative treatments are proposed, it is expected that around 10 million deaths each year could be caused by drug-resistant microorganisms by 2050. Currently, lipid nanoparticles (LNPs) have emerged as promising carriers for delivering a wide variety of molecules with interesting antimicrobial, antifungal or anticancer properties. Different generations of LNPs, such as solid lipid nanoparticles, nanostructured lipid carriers, liposomes, or lipid–polymer hybrid nanoparticles, were developed to increase the physical stability and the bioavailability of cargo drugs. Those systems provide complex architectures with targeting molecules, increasing drug loading, co-loading of synergetic drugs, and tailorable surfaces that could be powerful weapons to treat bacterial infections.
This Special Issue invites articles to present the recent advances in the development of lipid NPs with particular biological activities in the biomedical field. The Special Issue is intended to serve as a useful repository with new significant approaches to challenge the global advances of drug-resistance diseases caused by different microorganisms or even cancer cells.
Dr. Germán A. Islan
Dr. Boris Rodenak Kladniew
Guest Editor
Manuscript Submission Information
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Keywords
- lipid nanoparticles
- nanostructured carriers
- colloidal systems
- targeted drug delivery
- antimicrobial activity
- anticancer treatment
- biofilms
- antibiotic resistance
