Targeted Drug Delivery for Diagnostic and Therapeutic Applications
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 20 July 2024 | Viewed by 3071
Special Issue Editors
Interests: cancer therapy; gene delivery; contrast agents; magnetic resonance imaging; photothermal treatment; cell-based drug-delivery systems
Special Issue Information
Dear Colleagues,
Cancer is the second leading cause of death after cardiovascular diseases in developed countries. Despite rapid medicinal and pharmaceutical chemistry developments, chemotherapy is still a significant challenge. In the last decade, the development of effective targeted drug delivery systems for treating cancer has been a top priority in biomedical technology.
Targeted drug delivery is a system for specifying the drug moiety directly into its targeted body area (organ, cellular, and subcellular level of specific tissue) to overcome the specific toxic effect of conventional drug delivery, thereby reducing the amount of drug required for therapeutic efficacy. This targeted strategy enriches the concentration of the therapeutic agent in cells/tissues; as a result, low doses can be used, particularly if there is a contradiction between the therapeutic activity and the toxic effects of the agent. Increasing the concentration of therapeutic agents in the target location also improves their therapeutic index by enhancing the efficacy and/or increasing the tolerability in biological systems. Thus, targeted drug delivery is a priority approach in modern pharmacology.
This Special Issue intends to provide a forum for original research articles and reviews on the development of targeted drug delivery approaches. We invite researchers to share their ideas and results related to the development of drug delivery platforms and their potential application in treatment and diagnostics.
Dr. Nina Kostevšek
Dr. Georgy Mikhaylov
Guest Editors
Manuscript Submission Information
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Keywords
- drug delivery
- theranostics
- nanocarriers
- cancer treatment
- therapeutic nanoparticles
- targeting
- liposomes
- nanosomes
