Pharmaceutical Technology and Formulations for the Treatment of Eye Diseases
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Clinical Pharmaceutics".
Deadline for manuscript submissions: 10 July 2024 | Viewed by 1933
Special Issue Editors
Interests: medical and surgical retina; AMD; uveitis
Special Issue Information
Dear Colleagues,
The eye is considered the second most complex organ in the body after the brain. This complexity results from a variety of different anatomical structures and many physiologically independent functions.
Ophthalmic formulations are specialized drug compositions, specifically designed and constructed for the delivery of drugs to the eye. Ocular drug delivery suffers from many barrier effects such as drug loss from the ocular surface, small penetration through the corneal layers, and rapid systemic absorption. For posterior eye diseases, conventional drug delivery systems, such as eye drops, suspensions and ointments are not suitable for attaining optimal treatment results. Other routes for ocular drug delivery are necessary such as intravitreal, subretinal or suprachoroidal routes. The challenge is thus to design a drug with a high therapeutic efficacy which can be administered with an optimal concentration to the target region of the eye.
The aim of this Special Issue is to highlight the newest developments in pharmaceutical ophthalmic formulations, showcasing their progress in improving bioavailability and drug duration into the eye, as well as enhancing delivery to the targeted compartment of the eye.
Prof. Dr. Stephanie Baillif
Dr. Luc Demange
Guest Editors
Manuscript Submission Information
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Keywords
- delivery route
- formulation
- durability
- bioavailability
- controlled ocular drug delivery
- ocular inserts
- implants
- gene therapy
