Nano and Microdevices for Targeted Drug Delivery
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 1549
Special Issue Editors
Interests: oral drug delivery; microdevices; targeted delivery; drug formulations; vaccine delivery; peptide delivery
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
For many decades, drug delivery vehicles have consisted of particles, for example, prepared from lipids, polymers or a combination of the two. Often, these systems are sufficient to deliver drugs to their target, but for some drugs, more advanced delivery vehicles are needed to obtain sufficient absorption and bioavailability.
Within the last 10 years, top-down methods for creating nano- and microdevices have been suggested to be promising approaches for delivering drugs. The devices appear to be able to provide a more targeted delivery compared to, for example, particulates. These novel drug delivery systems are able to a) provide best-in-class protection of drugs from aggregation and acidic and enzymatic degradation, b) improve bioavailability, c) overcome physiologic barriers against drug absorption, d) prolong residence time, and e) enhance membrane permeability and migrate deep into the mucus layer. Devices have been used for delivering drugs, e.g., via the oral, buccal and pulmonary route of administration, but also via injections.
This Special Issue aims to provide an update on current and recent progress within nano- and microdevices for the delivery of drugs, vaccines and bioactives. Papers focusing on the design of the devices, fabrication, their characterization, drug encapsulation, drug release, and in vitro and in vivo studies are all of interest. Other relevant topics including microfabrication techniques amd 3D printing devices for targeting drug delivery are also welcome. Experimental, theoretical. and review articles are all considered.
Prof. Dr. Line Hagner Nielsen
Dr. Tijana Maric
Guest Editors
Manuscript Submission Information
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Keywords
- nano- and micromotors
- nano- and microdevices
- drug delivery systems
- 3D printing
- patches
- microfabrication
- bioavailability
- bioimaging
- nano- and microtechnology
- drug release
- drug targeting
