Special Issue "Pharmaceutical Formulation for Improving Oral Bioavailability"

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmacokinetics and Pharmacodynamics".

Deadline for manuscript submissions: 20 August 2023 | Viewed by 110

Special Issue Editor

Centre for Post-Graduate Studies and Research in Pharmaceutical Sciences, Shri G.H. Patel Pharmacy Building, Faculty of Pharmacy, The Maharaja Sayajirao University of Baroda, Vadodara 390002, Gujarat, India
Interests: novel drug delivery system; drug targeting; oral bioavailability enhancement approaches; transdermal drug delivery system

Special Issue Information

Dear Colleagues,

Drug delivery through oral administration is the most preferred mode of drug delivery. However, the main reason for a number of drugs not being available in oral dosage forms is their poor oral bioavailability. Various factors, such as low solubility, low permeability, inappropriate partition coefficient, and extensive hepatic and pre-systemic metabolism and degradation in the gastrointestinal tract, are mainly responsible for the poor oral bioavailability of drugs. Moreover, orally administered drugs may have different absorption windows based on their ability to remain unionized in a particular segment of GIT. Depending on the reason for poor oral bioavailability, various formulation approaches can be used for the enhancement of solubility and permeability, avoidance of first pass metabolism and inhibition of efflux mechanisms, targeting the drug to its absorption window, etc. This themed Special Issue aims to include research/review articles aimed at formulation approaches for oral bioavailability enhancement.    

Dr. Hetal Thakkar
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • oral bioavailability
  • solubility enhancement
  • permeability enhancement
  • avoidance of first pass metabolism
  • gastroretentive drug delivery system for bioavailability enhancement
  • liquisolid compacts/inclusion complexation

Published Papers

This special issue is now open for submission.
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