Nano-Drug Carriers Based on Membrane Fluidity
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 1107
Special Issue Editor
Interests: membranes; lipid nano-particles; carrier-membrane interactions
Special Issue Information
Dear Colleagues,
Cell membranes undergo profound transformations during the evolution of various pathologies. These transformations may provide new biomarkers or new therapeutic targets. Modifications in the type or in the density of various receptors or sugars at the cell surface have already been used for targeting purposes, but modifications in the biophysical properties of the membranes, due to intimate changes in lipid composition, such as membrane fluidity, are still underexplored.
This special issue proposes to focus on advances and novelties in the conception and use of nano-drug carriers based on membrane fluidity or more generally membrane physical properties. Nanomedicines with controlled membrane composition, and thus controlled fluidity, are currently developed to maximize their biophysical interactions with membrane lipids of various pathologic targets. In the meanwhile, membrane fluidity seems to be a key factor in the conception of novel nanomedicines with increased stability in body fluids and reduced interaction with circulatory components.
Developing novel nanomedicines to deliver molecules with therapeutic potential, designed to enhance drug delivery and carrier stability in blood, based on membrane fluidity is a key issue and a promising strategy in therapeutics and research applications.
Dr. Ofélia Maniti
Guest Editor
Manuscript Submission Information
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Keywords
- nano-drug carriers
- membrane fluidity
- lipid nano-particles
- carrier stability in body fluids
- carrier-membrane interactions
- particle penetration in tissue
- particle biodistribution