Special Issue "Bioactive Peptides and Their Role in Drug Development"
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Biopharmaceutics".
Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 618
Special Issue Editors
Interests: protein chemistry; proteomics; natural products; ethnobotany; ethnomedicine; environmental remediation
2. LEPABE—Laboratory for Process Engineering, Environment, Biotechnology & Energy, Faculty of Engineering, University of Porto, 4200-465 Porto, Portugal
Interests: biofilms; Candida; AMR; antifungal resistance; gene regulation; mechanism of action; bacteria, polymicrobial biofilm; alternative treatment; infection
Special Issues, Collections and Topics in MDPI journals
Interests: natural products; ethnopharmacology; plant extracts; bioactivity; phytochemistry
Special Issue Information
Dear Colleagues,
We are pleased to invite you to participate in this Special Issue of Pharmaceutics titled “Bioactive Peptides and Their Role in Drug Development”. This Special Issue is dedicated to the publication of original research articles, reviews and short communications addressing all aspects of the discovery and characterization of bioactive peptides, their biological function and mechanism and their uses in the development of drugs, pharmaceuticals, and nutraceuticals.
Peptides are short polymers comprising 2–50 amino acid monomers. Bioactive peptides are considered as biomolecules, which are inherently buried inside proteins and become active upon cleavage or proteolysis. Many groups of bioactive peptides are found in microorganisms, plants, marine invertebrates etc., supporting these organisms in their survival and acting as defense molecules against pathogens and external insults. Naturally occurring bioactive peptides play a vital role in many regulatory functions and exhibit various types of bioactive properties, such as antimicrobial, antihypertensive, and antioxidant activities; anti-aggregation; ability to bind minerals; anti-obesity, antidiabetic and antiaging effects etc. The synthesis and degradation of proteins in various organisms gives rise to a complex pool of bioactive peptides having several functions. Additionally, many bioactive peptides are generated by recombinant synthesis and proteolytic digestion by several enzymes. The development of solid-phase peptide synthesis has provided us with excellent opportunities to tailor and develop highly efficient bioactive peptides.
Thus, this Special Issue aims to highlight recent advances in all aspects of state-of-the-art analytical techniques and methods for peptides, such as sample preparation, separation and detection as well as data processing, as well as the various applications of peptides. We particularly welcome manuscripts focusing on functional and structural aspects of interactions between peptides and other biological molecules, leading to the development of pharmaceutical drugs and nutraceuticals, as well as their contribution to other biologically relevant entities. We also welcome manuscripts describing the discovery of novel peptides having multiple bioactivities.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:
- Novel peptides with multiple bioactive properties.
- Peptide–protein interactions leading to drug developments.
- Peptide–drug interactions outlying the mechanism of interaction.
- Peptides with chaperoning properties outlying the mechanism.
- Peptide engineering to develop more efficient bioactive peptides.
We look forward to receiving your contributions.
Dr. Alok Kumar Panda
Dr. Célia F. Rodrigues
Dr. Sujogya Kumar Panda
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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