Nanosystems for the Delivery of Natural Products

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: 30 June 2024 | Viewed by 1705

Special Issue Editors


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Guest Editor
College of Pharmaceutical Sciences, Food and Nutrition, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil
Interests: pharmaceutical biotechnology; antitumor compounds; cancer stem cell

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Guest Editor
Department of Pharmaceutical Sciences, Federal University of Paraíba, João Pessoa 58051-900, PB, Brazil
Interests: nanotechnology; natural Products; pharmaceutical biotechnology; biomolecular interaction
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
College of Pharmaceutical Sciences, Food and Nutrition, Federal University of Mato Grosso do Sul, Campo Grande 79070-900, Brazil
Interests: formulation; nanotechnology; microemulsions; nanoemulsions; nose-to-brain delivery; transdermal delivery; natural oils; characterization of nanostructures

Special Issue Information

Dear Colleagues,

Over the last few years, ethnopharmacology has been a valuable tool for identifying therapeutic natural products (NPs). However, the in natura use of NPs still accounts for relevant drawbacks, such as poor compliance, biopharmaceutical limitations, undesirable pharmacokinetics, and relevant toxicity. At present, nanotechnology is a popular approach to overcoming the limitations of complex or isolated active ingredients from natural extracts. The advances of nanostructured NP-based formulations have improved the potential application of synthetic and natural molecules, oils, and/or extracts in several disorders by improving solubility, decreasing the dosage, reducing toxicity, overcoming biological barriers, and so on. Among the several existing nanostructures made of NPs, a few can be highlighted, such as micelles, polymeric nanoparticles, solid lipid nanoparticles, nanostructured lipid carriers, nanoemulsions, microemulsions, liposomes, and liquid crystals, among others. Therefore, this issue is dedicated to research on the development, characterization, stability, and/or biological activity evaluation of nanosystems for the delivery of NPs and molecules from NPs.

Prof. Dr. Edgar Julian Paredes-Gamero
Prof. Dr. Francisco Humberto Xavier-Junior
Prof. Dr. Éverton Do Nascimento Alencar
Guest Editors

Manuscript Submission Information

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Keywords

  • lipid-based nanosystems
  • polymer-based nanosystems
  • hybrid nanosystems
  • colloidal systems
  • natural products

Published Papers (1 paper)

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Review

20 pages, 3144 KiB  
Review
Recent Trends in Curcumin-Containing Inorganic-Based Nanoparticles Intended for In Vivo Cancer Therapy
by Douglas Dourado, Júlio Abreu Miranda, Matheus Cardoso de Oliveira, Danielle Teixeira Freire, Francisco Humberto Xavier-Júnior, Edgar Julian Paredes-Gamero and Éverton do Nascimento Alencar
Pharmaceutics 2024, 16(2), 177; https://doi.org/10.3390/pharmaceutics16020177 - 26 Jan 2024
Cited by 1 | Viewed by 1313
Abstract
Curcumin is a natural compound that has been widely investigated thanks to its various biological properties, including antiproliferative. This molecule acts on different cancers such as lung, breast, pancreatic, colorectal, etc. However, the bioactive actions of curcumin have limitations when its physicochemical properties [...] Read more.
Curcumin is a natural compound that has been widely investigated thanks to its various biological properties, including antiproliferative. This molecule acts on different cancers such as lung, breast, pancreatic, colorectal, etc. However, the bioactive actions of curcumin have limitations when its physicochemical properties compromise its pharmacological potential. As a therapeutic strategy against cancer, curcumin has been associated with inorganic nanoparticles. These nanocarriers are capable of delivering curcumin and offering physicochemical properties that synergistically enhance anticancer properties. This review highlights the different types of curcumin-based inorganic nanoparticles and discusses their physicochemical properties and in vivo anticancer activity in different models of cancer. Full article
(This article belongs to the Special Issue Nanosystems for the Delivery of Natural Products)
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