Special Issue "Paediatric Dosage Forms: New Approaches to Old Challenges"

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmaceutical Technology, Manufacturing and Devices".

Deadline for manuscript submissions: closed (20 May 2023) | Viewed by 786

Special Issue Editors

Faculty of Medical and Health Sciences, University of Auckland, Auckland 1023, New Zealand
Interests: paediatric formulations; extemporaneous compounding; medicines for children
Department of Pharmaceutics, UCL School of Pharmacy, London WC1N 1AX, UK
Interests: pharmaceutics; formulation; patient centric; children; acceptability; palatability; taste masking

Special Issue Information

Dear Colleagues,

The paediatric population ranges from neonates to adolescents, with distinct differences in size, body composition, bodily function and sensory maturity across this age range. Many medicines for adults have potential applications for children but lack the dosing flexibility and demonstration of safety and efficacy through clinical trials to support use across the paediatric spectrum. Young children, especially neonates, handle drugs and excipients differently to older children and adults. With this in mind, a range of methods have been investigated to develop suitable patient-centric paediatric formulations.

The aim of this Special Issue of Pharmaceutics is to highlight new methodology related to paediatric product research and development. We invite researchers to publish their original research or review articles regarding the reformulation of off-patent drugs, novel excipients, administration devices and sensory pharmaceutics, with a focus on paediatrics.

Dr. Sara Hanning
Prof. Dr. Catherine Tuleu
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • paediatric/pediatric
  • neonate
  • off-patent reformulation
  • novel excipients
  • administration devices
  • sensory pharmaceutics
  • paediatric product research and development

Published Papers (1 paper)

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Review

Review
Exploring the Potential of Nanotechnology in Pediatric Healthcare: Advances, Challenges, and Future Directions
Pharmaceutics 2023, 15(6), 1583; https://doi.org/10.3390/pharmaceutics15061583 - 24 May 2023
Viewed by 486
Abstract
The utilization of nanotechnology has brought about notable advancements in the field of pediatric medicine, providing novel approaches for drug delivery, disease diagnosis, and tissue engineering. Nanotechnology involves the manipulation of materials at the nanoscale, resulting in improved drug effectiveness and decreased toxicity. [...] Read more.
The utilization of nanotechnology has brought about notable advancements in the field of pediatric medicine, providing novel approaches for drug delivery, disease diagnosis, and tissue engineering. Nanotechnology involves the manipulation of materials at the nanoscale, resulting in improved drug effectiveness and decreased toxicity. Numerous nanosystems, including nanoparticles, nanocapsules, and nanotubes, have been explored for their therapeutic potential in addressing pediatric diseases such as HIV, leukemia, and neuroblastoma. Nanotechnology has also shown promise in enhancing disease diagnosis accuracy, drug availability, and overcoming the blood–brain barrier obstacle in treating medulloblastoma. It is important to acknowledge that while nanotechnology offers significant opportunities, there are inherent risks and limitations associated with the use of nanoparticles. This review provides a comprehensive summary of the existing literature on nanotechnology in pediatric medicine, highlighting its potential to revolutionize pediatric healthcare while also recognizing the challenges and limitations that need to be addressed. Full article
(This article belongs to the Special Issue Paediatric Dosage Forms: New Approaches to Old Challenges)
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