Special Issue "Polymeric Micellar Formulations as Drug Carriers"
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Targeting and Design".
Deadline for manuscript submissions: closed (31 March 2023) | Viewed by 112
Special Issue Editors
Interests: molecular targeting; nonionic surfactants; self-assembled systems; drug delivery
Interests: surface; colloid; nano and polymer science; surfactant; block copolymer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Block copolymers, consisting of hydrophobic and hydrophilic blocks, aggregate in aqueous solutions to form micelles displaying spherical, ellipsoidal, cylindrical, or lamellar morphologies. Polymeric micelles offer high loading and solubilization capacity for hydrophobic drugs. Depending upon the polarity of the solubilizate, it can be located at the (a) micelle–water interface, (b) space between the headgroups, (c) palisade layer, or (d) inner core. The structure of micelles can be substantially altered by the incorporation of surfactants, small molecules, polymers, or other organic additives. Resultant interactions can be exploited to change the critical micelle concentration (CMC) of the amphiphile and architecture of aggregates. Interestingly, headgroups can be functionalized to enable site-specific drug-targeting applications.
This Special Issue of Pharmaceutics focuses on articles and reviews related to polymeric micelles. Emphasis will be placed on the development of functionalized block copolymers and their application in targeted drug delivery.
We look forward to receiving your contributions.
Dr. Sanjay Tiwari
Prof. Dr. Pratap Bahadur
Guest Editors
Manuscript Submission Information
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Keywords
- self-assembly
- solubilization
- hydrophobic drugs
- drug targeting
- core-shell micelles
- drug delivery
