Special Issue "Advances in Bioactive Peptides from Natural Sources: Characterization, Biological Targets and Promising Applications"

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Biopharmaceutics".

Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 307

Special Issue Editors

LAFMOL–Laboratory of Functional and Molecular Studies in Physiopharmacology, Department of Biophysics and Physiology, Federal University of Piauí, Teresina 64049-550, Brazil
Interests: bioactive peptides; cardiovascular; diabetes; dyslipidemia; endothelium; hypertension; medicinal plants; natural products; pharmacology; preclinical toxicology; vasorelaxant
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Research Center in Applied Morphology and Immunology (NuPMIA), Faculty of Medicine (FM), University of Brasília (UnB), Brasília 70910-900, DF, Brazil
Interests: biotechnology; bionanotechnology; bioprospection; biomolecules; health and environment
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LAQV/REQUIMTE, Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal
Interests: secondary metabolites; natural antioxidants; in vitro, in vivo, and in silico models; structure–activity relationship; natural product chemistry; oxidative stress and antioxidant defense; free-radical-mediated chain reactions; extraction and separation methods; antioxidant ingredients and biomaterials
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Special Issue Information

Dear Colleagues,

Venomous animals are considered specialized predators which have developed the most sophisticated apparatus regarding the chemistry and pharmacology of bioactive peptides, with a wide range of toxins with incredible structural and functional diversity and directed against a variety of pharmacological targets and with potential therapeutic applications. For example, studies on the pathophysiological mechanisms of envenoming and molecular characterization of toxins from the Bothrops jararaca snake venom resulted in the relevant discovery of bradykinin and bradykinin-potentiating peptides (BPPs), recognized by the first natural inhibitors of angiotensin I-converting enzyme (ACE) and model for the development of captopril, the first ACE inhibitor and the first commercially available drug for the treatment of arterial hypertension. In this sense, several peptides obtained from the venoms of amphibians, snakes, scorpions, and spiders have been reported in the literature as important bioactive compounds with important pharmacological effects and potential therapeutic applications. The aim of this Special Issue is to report current advances in bioactive peptides from natural sources, focusing on their characterization, biological targets, and promising applications. We are pleased to invite you to submit original research articles and reviews. Research areas may include (but are not limited to) the discovery and characterization of novel bioactive peptides, including pharmacological studies and development of bioproducts.

We look forward to receiving your contributions.

Dr. Daniel Arcanjo
Prof. Dr. José Roberto de Souza de Almeida Leite
Dr. Alexandra Plácido
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • bioactivity
  • synthesis
  • pharmacology
  • toxicology
  • immunogenicity
  • snake venom
  • scorpion venom
  • skin secretion
  • nanoparticles
  • bioassays

Published Papers

There is no accepted submissions to this special issue at this moment.
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